Initial and Long-term Results in the Management of Primary Chest Wall Neoplasms

Surgical therapy of primary malignant bone tumours and soft tissue sarcomas of the chest wall: a two-institutional experience

“…Further, small tumour size increases the possibility of curative treatment [1]. Sarcomas of the chest wall (soft tissue or bone) with involvement of ribs or sternum, or the overlying soft tissues, are rare entities, with chondrosarcomas as the most frequent ones [1][2][3][4][5][6][7][8][9][10][11][12]. Compared to osteosarcomas or Ewing's sarcomas, an effective chemotherapy for chondrosarcomas does not exist.…”

“…Compared to osteosarcomas or Ewing's sarcomas, an effective chemotherapy for chondrosarcomas does not exist. Furthermore, this entity is also relatively radio insensitive [8][9][10]. Therefore, the main treatment modality of choice is early wide resection.…”

“…Overall, information about treatment and oncological outcome of sarcomas of the chest wall is limited [2,[8][9][10][11][12]. Recently, Widhe and Bauer [5] showed that patients with delayed diagnosis of chondrosarcomas of the chest had significantly higher risk of tumour-related deaths.…”

“…On the other hand, King et al [7] showed a significantly better prognosis for chondrosarcomas of the chest wall compared to malignant fibrous histiocytomas, and Burt et al [6,9] reported a significantly longer survival rate for chondrosarcomas compared to osteosarcomas. Nevertheless, synchronous or metachronous diagnosis of metastases in lung, liver and/or bone is further associated with a significantly worse prognosis [6,[8][9][10]12].…”

Soft Tissue Sarcomas

“…The risk for local recurrence is approximately 20% in operations with such wide margins. The same surgical principles are applied to sarcomas in the extremities and sarcomas localized to the trunk wall (32)(33)(34)(35)(36)(37)(38)(39)(40)(41).…”