Abstract:The objective of the current work to evaluate the role of metformin in inhibiting the tamoxifen induced endometrial changes in diabetic patients with ER-positive breast cancer, a case-control study, carried out between December 2018 to May 2019, forty diabetic women in postmenopausal phase with ER+ breast cancer on tamoxifen (20mg/day), metformin (1700 mg/day) GROUP A, and 40 diabetic patients with ER+ breast cancer on the same dose of tamoxifen, but other hypoglycemic agent GROUP B, were selected as co… Show more
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