Inhibitory neuron map of sevoflurane induced neurotoxicity model in young primates
Yixuan Niu,
Yanyong Cheng,
Zhengjie Miao
et al.
Abstract:IntroductionSevoflurane, one of the most commonly used anesthetic agents in children, may induce neuronal dysfunction and cognitive impairment. Exposure to sevoflurane might induce an imbalance between neural excitation and inhibition which could be a mechanism behind anesthesia-induced cognitive and affective dysfunctions. However, the underlying mechanisms remain unclear.MethodsIn this study, we used two rhesus macaques in the control group, and one rhesus macaques in the anesthesia group. We employed single… Show more
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