Inhibitory effects of grape seed extract on lipases

Moreno, Diego A.; Ilić, Nebojša; Poulev, Alexander; Brasaemle, Dawn L.; Fried, Susan K.; Raskin, Ilya

doi:10.1016/s0899-9007(03)00167-9

Cited by 219 publications

(158 citation statements)

References 34 publications

Supporting

Mentioning

149

Contrasting

Unclassified

Order By: Relevance

“…This finding is supported by Moreno et al (2003) who found that grape seed extract inhibited lipase activity in a dose-dependent manner. There may be an indirect association between lower lipase activity and allelopathic inhibition of water uptake.…”

Section: Discussionsupporting

confidence: 64%

Allelopathic effect of ginger on seed germination and seedling growth of soybean and chive

Han

Pan

et al. 2008

Scientia Horticulturae

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 64%

Allelopathic effect of ginger on seed germination and seedling growth of soybean and chive

Han

Pan

et al. 2008

Scientia Horticulturae

View full text Add to dashboard Cite

“…Wren et al (2002) found feeding GSE to rats at levels of up to 2.0% for a period of 90 days resulted in all groups of animals gaining weight during the trial and that food consumption in the 2.0% group was significantly higher than that of the control group. However, Moreno et al (2003) and Vogel et al (2004) reported decreased BWs in mice and rats while other researchers (Yamakoshi et al, 2002;Gontheir et al, 2003) found GSE treatments did not produce any significant changes in BW in rats.…”

Section: Resultsmentioning

confidence: 91%

Feeding grape seed extract to horses: effects on health, intake and digestion

Davies

Krebs

Barnes

et al. 2009

Animal

View full text Add to dashboard Cite

A feeding trial involving four Thoroughbred race horses was undertaken to establish whether inclusion of grape seed extract (GSE) in the diet of horses undergoing mild exercise had any effects on their general health, intake and digestion. Supplementation with GSE had no effect on either feed or water intake of the horses and the supplement was readily palatable to the horses at all levels of inclusion. Feeding GSE caused no adverse effects in terms of animal health (temperature, pulse and respirations rates), and there were some positive effects related to a presumed alteration in fermentation in the hindgut. Feeding GSE increased faecal pH, changing from acid faeces (pH 6.6) when no GSE was fed to neutral faeces (pH 7.0) when 150 mg GSE/kg body weight (BW) was fed. In addition, blood glucose concentrations were significantly ( P , 0.05) decreased when GSE was fed at 100 and 150 mg/kg BW (5.50 6 0.26 and 5.32 6 0.72 mmol/l, respectively) compared with the control diet (5.77 6 0.31 mmol/l). The actual mechanisms causing these alterations are yet to be elucidated, but could have important implications for the prevention of acidosis.

show abstract

“…The BRE and RRE can significantly reduce (between 40 and 50%) serum triglycerides and cholesterol in STZ-induced diabetic rats. Proanthocyanidins were able to inhibit pancreatic lipase activity and consequently reduce the level of plasma triglycerides 27 . The lipid lowering effects of anthocyanins was also in well agreement with the studies by Tsuda et al 28 .…”

Section: Discussionmentioning

confidence: 99%

Anti-hyperglycaemic and anti-hyperlipidaemic effects of black and red rice in streptozotocin-induced diabetic rats

Tantipaiboonwong¹,

Pintha²,

Chaiwangyen³

et al. 2017

ScienceAsia

View full text Add to dashboard Cite

Increasing numbers of diabetic patients, especially those with type II, can link their condition to changes in eating habits. Black rice and red rice are not only a source of carbohydrate but also rich sources of antioxidants, especially proanthocyanidins and anthocyanins. This study determines the effect consuming a black rice extract (BRE) or a red rice extract (RRE) on streptozotocin-induced diabetic rats. Blood levels of glucose, triglycerides, and cholesterol in the diabetic group were determined and compared to that of the control group. The results demonstrate that consumption of BRE, 50 mg/kg body weight (BW), or RRE, 100 mg/kg BW, could significantly reduce the blood glucose level of the diabetic rats after eight weeks. Consumption of BRE, 100 mg/kg BW or RRE, 50 mg/kg BW, also clearly decreased the triglyceride level. The cholesterol level in the diabetic group fed with BRE or RRE decreased as well. Thus daily consumption of black rice, red rice, or having their extracts in food supplements may prevent the onset of diabetes.

show abstract

Inhibitory effects of grape seed extract on lipases

Cited by 219 publications

References 34 publications

Allelopathic effect of ginger on seed germination and seedling growth of soybean and chive

Allelopathic effect of ginger on seed germination and seedling growth of soybean and chive

Feeding grape seed extract to horses: effects on health, intake and digestion

Anti-hyperglycaemic and anti-hyperlipidaemic effects of black and red rice in streptozotocin-induced diabetic rats

Contact Info

Product

Resources

About