Inhibitory effects of children’s toothpastes on Streptococcus mutans, Streptococcus sanguinis and Lactobacillus acidophilus

Evans, Alana; Leishman, Shaneen; Walsh, L. J.; Seow, W.K.

doi:10.1007/s40368-014-0159-3

Cited by 28 publications

(41 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The antibacterial effects of chlorhexidine and cetylpyridinium chloride on planktonic bacteria have been verified in several previous studies Sreenivasan et al, 2013, Koljalg et al, 2002, Kitagawa et al, 2016, Andre et al, 2011, Evans et al, 2015. Koljalg et al Koljalg et al, 2002 studied the susceptibility of various bacterial isolates to chlorhexidine, and reported that Gram-positive bacteria were more susceptible than Gram-negative bacteria.…”

Section: Discussionmentioning

confidence: 64%

See 1 more Smart Citation

Susceptibility of Oral Streptococci to Chlorhexidine and Cetylpyridinium Chloride

Yeon

Young

2019

Biocontrol Sci.

View full text Add to dashboard Cite

Although the most common bacteria in the supragingival plaque are Gram-positive streptococci, no extensive investigations have been conducted into the susceptibility of these species to chlorhexidine and cetylpyridinium chloride. Therefore, in this study, we investigated the susceptibility of 80 streptococcal strains in planktonic or biofilm states to these two antimicrobial agents. The minimum inhibitory concentration MIC and minimum bactericidal concentration MBC of the planktonic streptococci were measured using the microdilution method, as were the minimum biofilm inhibitory concentration MBIC and minimum biofilm eradication concentration MBEC measured on streptococcal biofilms formed on 96-well plates. In all species, the MIC, MBC, MBIC, and MBEC values were higher for chlorhexidine than for cetylpyridinium chloride, with sensitivity values varying according to species. For chlorhexidine, the MIC, MBC, and MBIC values showed statistically significant differences among species. However, only MBEC values showed statistically significant differences for cetylpyridinium chloride. The MIC against Streptococcus mutans and the MBC against Streptococcus salivarius were significantly lower than those against the other species. With the exception of a few species, most of the bacterium susceptibility values were higher in the biofilm state than in the planktonic state.

show abstract

Section: Discussionmentioning

confidence: 64%

“…of cetylpyridinium chloride compared with chlorhexidine Sreenivasan et al, 2013, Andre et al, 2011, Evans et al, 2015 . The MIC results of our experiment showed similar values as those observed by previous studies for oral streptococci.…”

Section: Relationship Between the Susceptibility Values Of Planktonicmentioning

confidence: 99%

Susceptibility of Oral Streptococci to Chlorhexidine and Cetylpyridinium Chloride

Yeon

Young

2019

Biocontrol Sci.

View full text Add to dashboard Cite

show abstract

“…In addition to MGS, other microorganisms such as S. sanguinis, S. oralis and S. gordonii, can also be found in the dental biofilm. 27 Cariogenic associations were observed when multispecies biofilms were formed with Bifidobacterium sp. and S. mutans or S. sobrinus, showing that such combinations of microorganisms had a much stronger enamel demineralizing capacity than monospecies biofilms.…”

Section: Oral Bacterial Biofilmsmentioning

confidence: 99%

Propriedades antibacterianas e anticariogênicas do xilitol: uma revisão da literatura

Cabral-Oliveira

Freires

Oliveira

et al. 2018

Rev. Bras. Odontol.

View full text Add to dashboard Cite

Objective: the purpose of this study was to review some properties of xylitol as an antimicrobial agent and the role of this sugar alcohol in the prevention and control of dental caries activity. Material and Methods: the study was based on PubMed scientific papers, in addition of evaluating older researches, to obtain a more complete view of this polyol, encompassing its biochemical, antibacterial, antibiofilm and toxic properties, as well as its different forms of use. Results: the study carried out highlighted the positive characteristics of xylitol in relation to its use in humans and its possible therapeutic use as a substance for the prevention and control of caries disease. Conclusion: It was concluded that, though the scientific documentation that reinforce its efficiency in caries prevention, some authors still do not consider the clinical evidence as satisfactory about the effects of xylitol, and recommend better controlled clinical investigations, especially in relation to the prolonged use of this polyol, in order to provide more conclusive data.

show abstract

“…[11][12][13][14] Estudos laboratoriais in vitro em geral têm comprovado a eficácia do xilitol em cepas de S. mutans, 9,[15][16][17] no entanto, outros estudos somente verificam sua ação, quando associado a fluoretos ou outros agentes anitimicrobianos. [18][19][20][21][22] Portanto, o objetivo deste estudo foi avaliar a eficácia in vitro de um dentifrício não fluoretado (marca Orgânico Natural®) na inibição da cepa de S. mutans, um dos principais agentes etiológicos no processo da cárie dentária.…”

Section: Introductionunclassified

Eficácia de um dentifrício sem flúor no controle de Streptococcus mutans in vitro

Schardong¹,

Bertuol²,

Mercado³

et al. 2018

Rev. da Fac. de Odontologia, UPF

View full text Add to dashboard Cite

Objetivo: avaliar a eficácia de um dentifrício, que contém em sua composição extratos vegetais e xilitol para inibição de Streptococcus mutans (UA159). Materiais e método: para verificação da atividade antimicrobiana, foram realizados ensaios in vitro de difusão de ágar, baseados na metodologia da norma M2A8 Anvisa. O estudo foi feito utilizando inóculo de 108 UFC/mL da cepa de S. mutans. O princípio básico foi a difusão de uma solução de dentifrício na superfície do ágar a partir de um disco impregnado. O ensaio foi realizado utilizando como controle negativo água deionizada estéril e como controle positivo clorexidina 0,12%, e foram comparados aos dentifrícios Orgânico Natural® e Colgate Total 12®. O resultado foi analisado a partir da medição dos halos de inibição (mm). Resultados: a clorexidina 0,12% teve maior halo de inibição (21,08 ± 1,02), seguida do dentifrício Orgânico Natural® (11,33 ± 4,35) e do dentifrício Colgate Total 12 (3,93 ± 4,67) P<0,05. Conclusão: a inibição da cepa de S. mutans evidenciada neste ensaio in vitro demonstra o potencial antimicrobiano do dentifrício Orgânico Natural®, mesmo como um possível auxiliar no controle do biofilme dental cariogênico.

show abstract

Inhibitory effects of children’s toothpastes on Streptococcus mutans, Streptococcus sanguinis and Lactobacillus acidophilus

Abstract: Sodium lauryl sulphate is the major bacterial inhibitory compound in children's dentifrices.

Cited by 28 publications

References 38 publications

Susceptibility of Oral Streptococci to Chlorhexidine and Cetylpyridinium Chloride

Susceptibility of Oral Streptococci to Chlorhexidine and Cetylpyridinium Chloride

Propriedades antibacterianas e anticariogênicas do xilitol: uma revisão da literatura

Eficácia de um dentifrício sem flúor no controle de Streptococcus mutans in vitro

Contact Info

Product

Resources

About