1992
DOI: 10.1016/0378-4320(92)90021-5
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Inhibitory effect of naloxone on luteinizing hormone secretion in immature gilts

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“…In pregnant gilts, naloxone increases LH (Szafranska and others 1994) and reduces PRL (Szafranska and Tilton 1995) at day 40 of pregnancy; however, at day 70, LH and PRL concentrations have been shown to be similar before and after treatment. Other studies (Prunier 1992) have confirmed that naloxone inhibits LH in gilts, suggesting that modulation of LH secretion by opioids varies during sexual maturation: it is inhibitory in neonatal females and is stimulatory in adult females.…”
mentioning
confidence: 84%
“…In pregnant gilts, naloxone increases LH (Szafranska and others 1994) and reduces PRL (Szafranska and Tilton 1995) at day 40 of pregnancy; however, at day 70, LH and PRL concentrations have been shown to be similar before and after treatment. Other studies (Prunier 1992) have confirmed that naloxone inhibits LH in gilts, suggesting that modulation of LH secretion by opioids varies during sexual maturation: it is inhibitory in neonatal females and is stimulatory in adult females.…”
mentioning
confidence: 84%