Inhibitory Effect of Ginger Extract on Candida albicans

Atai, Zahra; Atapour, Manijeh; Mohseni, Maryam

doi:10.3844/ajassp.2009.1067.1069

Cited by 59 publications

(43 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, only the methanolic and benzyl alcohol extract of ginger had activity on A. niger. An inhibition zone diameter of 11 mm was obtained with ethanolic extracts of ginger against C. albicans in a study conducted by Atai et al, 2009. Similarly, an IZD of 16 mm was obtained with ethanolic extracts of ginger against C. albicans in a study conducted by Supreetha et al, 2011 [24].…”

Section: Resultsmentioning

confidence: 99%

Evaluation of the Antifungal Activity of Aqueous and Alcoholic Extracts of Six Spices

Ikegbunam¹,

Ukamaka²,

Emmanuel³

2016

AJPS

View full text Add to dashboard Cite

Background: Nigeria is plagued with a variety of socioeconomic problems mainly poverty, poor access to quality healthcare and poor hygienic conditions resulting in the myriad of fungal infections that are frequently encountered in clinical practice. Method: The antifungal activity of aqueous, methanolic, propanolic and benzyl alcohol extracts of Capsicum annuum fruits and seeds, Capsicum chinense fruits and seeds, Aframomum melegueta pods and seeds, Allium sativum bulbs, Allium cepa bulbs and Zingiber officinale rhizomes on Candida albicans (yeast), Aspergillus niger (mould) and Trichophyton rubrum (dermatophyte) were evaluated by the agar well diffusion method. The aqueous and alcoholic filtered plant extracts were obtained by maceration, and also methanolic extracts were also obtained by Soxhlet extraction. The results were obtained by measuring the inhibition zone diameter in millimeters and were presented by subtracting the activity of the control. Results: Aqueous and methanolic extracts of Allium sativum gave the highest inhibition of the growth of Candida albicans (22 mm), followed closely by its propanolic extract with inhibition zone diameter of 15 mm, and also, propanolic extracts of Aframomum melegueta and Allium cepa gave inhibition zone diameters of 12 mm each. Soxhlet methanolic extract of Allium sativum had the highest inhibition of the growth of Aspergillus niger with an inhibition zone diameter of 25 mm, followed closely by Zingiber officinale Soxhlet methanolic extract with an inhibition zone diameter of 22 mm, also, the propanolic extract of Allium sativum gave an inhibition zone diameter of 21 mm, whereas Soxhlet methanolic extracts of Aframomum melegueta and Allium cepa gave an inhibition zone diameter of 19 mm each. The highest activity against Trichophyton rubrum was obtained with the Soxhlet methanolic extract of Allium sativum (39 mm), followed closely by its propanolic extract with an inhibition zone diameter of 27 mm. An inhibition zone diameter of 22 mm was recorded with the benzyl alcohol extract of Allium cepa, 22 mm with the Soxhlet methanolic extract of Aframomum melegueta and 19mm with the aqueous extract of Capsicum chinense seeds. Conclusion: The in-vitro inhibitory effects of these spice extracts indicated that the test spices could serve as potential candidates for developing new systemic and topical M. Ikegbunam et al. 119 antifungal drugs against the wide range of pathogenic fungal strains, and they could also serve as natural prophylaxis against the fungal infections.

show abstract

Section: Resultsmentioning

confidence: 99%

Evaluation of the Antifungal Activity of Aqueous and Alcoholic Extracts of Six Spices

Ikegbunam¹,

Ukamaka²,

Emmanuel³

2016

AJPS

View full text Add to dashboard Cite

show abstract

“…Ginger has been reported to exhibit antibacterial (M. N. J. Gulve & N. D. G. Gulve, 2010;Mohamed et al, 2016), antioxidant (Bellik, 2014), antibiofilm (Kim et al, 2013), anti-gastrointestinal cancer (Prasad & Tyagi, 2015) and antifungal properties (Ficker et al, 2003;Atai et al, 2009). As for O. stamineus, studies have reported on the antioxidant, anti-inflammatory (Akowuah et al, 2004;Yam et al, 2008), antifungal (Hossain et al, 2006) and antibacterial properties of this plant (Ho et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

In vitro Antibacterial Activity of Zingiber officinale and Orthosiphon stamineus on Enterococcus faecalis

Abidin¹,

Abdul-Wahab²,

Ghazi-Ahmad³

et al. 2017

JAS

View full text Add to dashboard Cite

This study evaluates the antibacterial effects of Zingiber officinale essential oil and Orthosiphon stamineus water extract against Enterococcus faecalis. The herbs were prepared in various concentrations to determine their minimum inhibitory concentrations (MIC) and growth inhibitory effect. Anti-adhesion activities of the herbs were determined by co-incubation with E. faecalis cultures for 6 and 24 h. Biofilm disruption activities were determined by adding the studied herbs into preformed E. faecalis biofilm. The effects on the morphology of E. faecalis grown as biofilm were studied using scanning electron microscopy (SEM). The MICs of ginger oil and O. stamineus extract were 0.31 and 25 mg/mL, respectively. Between the tested herbs, ginger exhibited greater inhibitory effects on the growth of E. faecalis grown in suspension mode. Both herbs generally showed anti-adhesion activities in inverse concentration-dependent manner. No significant biofilm disruption activities by both herbs were observed. SEM analyses showed E. faecalis cell surface changes in the treated biofilm. The studied herbs may have compromised the integrity of the bacterial cell membrane. These findings suggest that the studied herbs may have better antibacterial activities against E. faecalis in suspension mode compared to biofilm mode, with ginger oil showed greater antibacterial activity compared to O. stamineus extract.

show abstract

“…Ginger rhizome (Zingiber officinale Roscoe, Zingiberacae) is widely used in food condiments and medical herb around the world. Their compound has properties that improve the functioning of the immune system, anti-tumorigenic, anti-inflammatory, anti-apoptosis, antihyperglycemia, anti-lipidemic (Ali et al, 2008) and antifungal activities (Atai et al, 2009). Recently, instead of antibiotics, we reported that DFG possesses growth-promoting qualities in broiler chicken (Incharoen et al, 2010) and egg-productionpromoting qualities in layer chickens (Incharoen and Yamauchi, 2009).…”

Section: Introductionmentioning

confidence: 99%

No Damage of Dietary Dried Fermented Ginger Diet without Antibiotics on Growth Performance in Broilers Reared in Tropical Area

Khonyoung¹

2011

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

Problem statement:The experiment was carried out to determine whether the dietary Dried Fermented Ginger (DFG) has no affecting damage on broiler growth performance and can also be applicable in tropical and subtropical area using basal diets without antibiotics. Approach: Three hundred and fifty 7-d-old Arbor Acres broiler chicks were divided into one basal diet group (control) and 6 experimental groups. The basal diets were adequately formulated, but not added with antibiotics. Among the 6 DFG groups, 3 groups were fed each basal diet supplemented with DFG at 0.25 (0.25 S), 0.5 (0.5 S) and 1% (1 S) levels from 7-42 days of age (starter groups). The remaining 3 DFG groups were fed the starter basal diet until 21 days of age. At 22 days of age, they were switched to finisher diet supplemented with DFG at 0.25 (0.25 F), 0.5 (0.5 F) and 1% (1 F), from 22-42 days of age (finisher groups). Results: Feed intake, body weight gain and feed efficiency were not significantly different among the groups (p>0.05). However, when the body weight gain of the control was expressed as an index of 100, the body weight gain index of the DFG groups was better than the control except the 0.25 S groups. Compared to the body weight gain index of the starter groups, they showed the better index. The values of feed efficiency were also better in all the experimental groups than in the control. Conclusion: The present results suggest that DFG can apply to tropical and subtropical area as a natural supplementation without antibiotics and it is better to supplement to basal diet during finisher stage (from 22 days old).

show abstract

Inhibitory Effect of Ginger Extract on Candida albicans

Cited by 59 publications

References 20 publications

Evaluation of the Antifungal Activity of Aqueous and Alcoholic Extracts of Six Spices

Evaluation of the Antifungal Activity of Aqueous and Alcoholic Extracts of Six Spices

In vitro Antibacterial Activity of Zingiber officinale and Orthosiphon stamineus on Enterococcus faecalis

No Damage of Dietary Dried Fermented Ginger Diet without Antibiotics on Growth Performance in Broilers Reared in Tropical Area

Contact Info

Product

Resources

About