Inhibitory effect of different fennel ( Foeniculum vulgare ) samples and their phenolic compounds on formation of advanced glycation products and comparison of antimicrobial and antioxidant activities

Salami, Maryam; Rahimmalek, Mehdi; Ehtemam, Mohammad Hossein

doi:10.1016/j.foodchem.2016.06.070

Cited by 51 publications

(28 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of this study are in agreement with a study of Salami et al 27 . They found high variation in composition of methanol extract in 23 fennel samples.…”

Section: Discussionsupporting

confidence: 94%

The effect of the aqueous and methanol fennel stem extracts (Foeniculum vulgare Miller) on isolated rat ileum contractility

Gocmanac-Ignjatovic¹,

Kitić²,

Radenković

et al. 2018

VOJNOSANIT PREGL

View full text Add to dashboard Cite

Background/Aim. The fennel (Foeniculum vulgare Miller, Apiaceae) has a long history of use as traditional herb medicine due to its carminative properties. The study was aimed to investigate the effects of aqueous and methanol fennel stem extracts on intestinal activity. Methods. Relaxant activity of aqueous and methanol fennel stem extracts was evaluated in vitro in three experimental models: spontaneous contraction, acetylcholine and potassium chloride (KCl)-induced contraction of an isolated rat ileum. The composition of aqueous and methanol fennel stem extracts was qualitatively analyzed using the high performance liquid chromatographic (HPLC) analysis. Results. In the presence of an aqueous fennel stem extract at a concentration of 3 mg/mL, the inhibition of the spontaneous contractions of isolated rat ileum was 35.05% ± 3.57%. In presence of a methanol fennel stem extract at the same concentration, the maximum reduction of the spontaneous contractions was 48.91% ± 6.31%. The extracts in a concentration-dependent manner significantly inhibited the acetylcholine and KCl induced contractions of the isolated rat ileum (p < 0.01). The following components were identified in fennel methanol stem extract: 3-caffeoylquinic acid, chlorogenic acid, 4-caffeoylquinic acid, 1,3-dicaffeoylquinic acid, rutin, miquelianin, quercetin heterosides, 1,5-dicaffeoylquinic acid, 1,4-dicaffeoylquinic acid, apigenin and rosmarinic acid. In an aqueous extract, their presence is found in trace amounts. Conclusion. The results of this study showed that the aqueous and methanol fennel stem extracts have spasmolytic effects on the intestinal smooth muscle and may be used for the control of intestinal motility.

show abstract

“…The results of this study are in agreement with a study of Salami et al 27 . They found high variation in composition of methanol extract in 23 fennel samples.…”

Section: Discussionsupporting

confidence: 94%

The effect of the aqueous and methanol fennel stem extracts (Foeniculum vulgare Miller) on isolated rat ileum contractility

Gocmanac-Ignjatovic¹,

Kitić²,

Radenković

et al. 2018

VOJNOSANIT PREGL

View full text Add to dashboard Cite

show abstract

“…Results showed that phenolic compounds significantly differed among cultivars. (Salami et al, 2016). In addition, Faudale et al (2008) confirmed that phenolic accumulation considerably varied between the different fennel extracts with the predominance of chlorogenic, neochlorogenic acids, and dicaffeoylquinic acids.…”

Section: Phenolic Compoundsmentioning

confidence: 70%

“…These results were comparable to those of Krizman, Dea, and Mirko () who noticed the presence of 3‐caffeoylquinic acid, chlorogenic acid, 4‐caffeoylquinic acid, 1,3‐dicaffeoylquinic acid, 1,5‐dicaffeoylquinic acid, 1,4‐dicaffeoylquinic acid, rosmarinic acid, eriocitrin, rutin, and miquelianin in fennel plants. A significant variation in chlorogenic acid, caffeic acid, p ‐coumaric acid, rutin, ferulic acid, 1,5‐dicaffeoylquinic acid, quercetin, and apigenin amounts was detected in methanolic seed extracts of 23 Iranian fennel samples (Salami et al, ). In addition, Faudale et al () confirmed that phenolic accumulation considerably varied between the different fennel extracts with the predominance of chlorogenic, neochlorogenic acids, and dicaffeoylquinic acids.…”

Section: Resultsmentioning

confidence: 99%

“…Fennel seed essential oil has valuable antibacterial, antifungal, and antioxidant activities (Ozcan, Chalchat, Arslan, Ates, & Unver, ; Singh, Maurya, De Lampasona, & Catalan, ). On the contrary, chlorogenic acid, caffeic acid, p ‐coumaric acid, rutin, ferulic acid, 1,5‐dicaffeoylquinic acid, quercetin, and apigenin are the phenolic components of fennel seeds having potent biological properties (Salami, Rahimmalek, & Ehtemam, ).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chemical composition and antioxidant potential of essential oil and methanol extract from Tunisian and French fennel ( Foeniculum vulgare Mill.) seeds

et al. 2019

View full text Add to dashboard Cite

This study was designed to examine the effect of provenance on the phytochemical and antioxidant properties of essential oil and methanolic extract from Tunisian and French fennel seeds (FFS). Analysis of the essential oil showed that although the same main compounds were found in Tunisian and FFS cultivars, some differences were present in their proportions allowing to classify them in two chemotypes. The first class was composed by trans‐anethole (63.41%–78.26%) for Tunisian cultivars and the second one by estragole (44.72%–88.92%) for French cultivars. The phenolic composition of all fennel seed extracts was characterized by its richness in quinic acid, 4‐O‐caffeoylquinic acid, p‐coumaric acid, and 4‐O‐caffeoylquinic acid. All fennel seed extracts showed a better antioxidant potential than their essential oils depending on the origin. Principal component analysis showed a dispersion of the cultivars on three groups depending on the chemotype diversity. Practical applications Recently, much attention has been focused on fennel due to the nutritional and health‐protective value of their seeds. Several studies have highlighted the importance of fennel seed extracts and essential oils as key ingredients rich in bioactive compounds serving in formulation of new functional food products. This investigation designed to examine the effect of provenance on phytochemical and antioxidant potentials of Tunisian and French fennel seed extracts and essential oils.

show abstract

“…The extracts were filtered before injection (0.22 μm). The HPLC elusion procedure was followed by Salami et al . method with some modifications.…”

Section: Experimental Setionmentioning

confidence: 99%

Essential Oil and Bioactive Compounds Variation in Myrtle (Myrtus communis L.) as Affected by Seasonal Variation and Salt Stress

Shoshtari

Rahimmalek

Hosseini³

2017

Chemistry & Biodiversity

Self Cite

View full text Add to dashboard Cite

The effect of different NaCl concentrations (control, 2, 4 and 6 dS/m) and three harvesting times in different seasons including spring (9 April), summer (5 July), and fall (23 September) was evaluated on essential oil (EO) yield, composition, phenolic, flavonoid content, and antioxidant activity of myrtle. Essential oil yield ranged from 0.2% in control and fall to 1.6% in moderate salinity (4 dS/m) and spring season. The main constituents obtained from gas chromatography/mass spectrometry analysis were α-pinene, 1,8-cineole, limonene, linalool, α-terpineol, and linalyl acetate in which α-pinene ranged from 11.70% in moderate and fall to 30.99% in low salinity (2 dS/m) and spring, while 1,8-cineole varied from 7.42% in high salinity (6 dS/m) and summer to 15.45% in low salinity and spring, respectively. Salt stress also resulted in an increase in total phenolic, flavonoid content, and antioxidant activity. The highest antioxidant activity based on DPPH radical scavenging activity, reducing power (FTC) and β-carotene/linoleic acid model systems was found in plants harvested in spring and summer in high stress condition. The lowest IC values obtained in 6 dS/m in spring (375.23 μg/ml) followed by summer (249.41 μg/ml) and fall (618.38 μg/ml). Eight major phenolic and flavonoid compounds were determined in three harvesting times using high performance liquid chromatography analysis. In overall, late harvesting time of myrtle in fall can lead to reduce the most of major EO components, while it can improve the amount of phenolic acids.

show abstract

Inhibitory effect of different fennel ( Foeniculum vulgare ) samples and their phenolic compounds on formation of advanced glycation products and comparison of antimicrobial and antioxidant activities

Cited by 51 publications

References 44 publications

The effect of the aqueous and methanol fennel stem extracts (Foeniculum vulgare Miller) on isolated rat ileum contractility

The effect of the aqueous and methanol fennel stem extracts (Foeniculum vulgare Miller) on isolated rat ileum contractility

Chemical composition and antioxidant potential of essential oil and methanol extract from Tunisian and French fennel ( Foeniculum vulgare Mill.) seeds

Essential Oil and Bioactive Compounds Variation in Myrtle (Myrtus communis L.) as Affected by Seasonal Variation and Salt Stress

Contact Info

Product

Resources

About