Inhibitory and nutrient use phenotypes among coexisting Fusarium and Streptomyces populations suggest local coevolutionary interactions in soil

Abstract

Summary Bacteria and fungi are key components of virtually all natural habitats, yet the significance of fungal‐bacterial inhibitory interactions for the ecological and evolutionary dynamics of specific bacterial and fungal populations in natural habitats have been overlooked. More specifically, despite the broad consensus that antibiotics play a key role in providing a fitness advantage to competing microbes, the significance of antibiotic production in mediating cross‐kingdom coevolutionary interactions has received relatively little attention. Here, we characterize reciprocal inhibition among Streptomyces and Fusarium populations from prairie soil, and explore antibiotic inhibition in relation to niche overlap among sympatric and allopatric populations. We found evidence for local adaptation between Fusarium and Streptomyces populations as indicated by significantly greater inhibition among sympatric than allopatric populations. Additionally, for both taxa, there was a significant positive correlation between the strength of inhibition against the other taxon and the intensity of resource competition from that taxon among sympatric but not allopatric populations. These data suggest that coevolutionary antagonistic interactions between Fusarium and Streptomyces are driven by resource competition, and support the hypothesis that antibiotics act as weapons in mediating bacterial–fungal interactions in soil.

Post-translational regulation of autophagy is involved in intra-microbiome suppression of fungal pathogens

“…Antagonistic interactions between members of Streptomyces and Fusarium are known to be largely mediated by antibiotics produced by Streptomyces [ 40 ]. To evaluate this, we first tested and confirmed that the S89 supernatant can suppress fungal growth and induce autophagy (Fig.…”

“…Due to missing plant resistance mechanisms, bacteria with antagonistic potential towards soil-borne fungi provide an alternative way to improve soil and plant health [ 14 ]. Here, members of the bacterial genus Streptomyces , which are known to produce a broad range of antimicrobial compounds and frequently coexist with Fusarium in natural niches [ 39 , 40 ], are among the most promising candidates. Exploration of the underlying mechanisms of intra-microbiome interactions between Streptomyces and Fusarium will enhance our understanding of healthy microbiomes [ 40 ].…”

“…Here, members of the bacterial genus Streptomyces , which are known to produce a broad range of antimicrobial compounds and frequently coexist with Fusarium in natural niches [ 39 , 40 ], are among the most promising candidates. Exploration of the underlying mechanisms of intra-microbiome interactions between Streptomyces and Fusarium will enhance our understanding of healthy microbiomes [ 40 ]. The objective of this study was to disentangle the interaction between two widespread components of the plant microbiota at the molecular level.…”

Investigating Useful Properties of Four Streptomyces Strains Active against Fusarium graminearum Growth and Deoxynivalenol Production on Wheat Grains by qPCR

“…In an effort to select novel Streptomyces strains able to counteract fungal and mycotoxin contamination in a wheat-Fusarium pathosystem, their survival on wheat grains and the potential inhibitory effect of a co-culture with the pathogen needs to be assessed. Indeed, biological interactions between Streptomyces and Fusarium are crucial to understand how possible disease control can be employed and exploited [27].…”

Soil microbes mediate the effects of nitrogen supply and co-inoculation on Barley Yellow Dwarf Virus in Avena sativa

“…We selected the host species and virus species because of their importance for agriculture (Mckirdy et al, 2002;Riedell et al, 2007) and the wide knowledge base provided by previous studies (Carrigan et al, 1983;Baltenberger et al, 1987;Power et al, 1991;Erion & Riedell, 2012;Lacroix et al, 2014). However, the host species does not naturally co-occur with the soil microbial communities sampled in this study, which may have limited the observed effects of microbe inoculum on plant growth and plant-pathogen interactions (Essarioui et al, 2020).…”