Inhibition of Urease by Sulfur Compounds

Ambrose, John F.; Kistiakowsky, G. B.; Kridl, Andrew G.

doi:10.1021/ja01157a083

Cited by 33 publications

(23 citation statements)

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“…However, evidence from this study corroborates previous studies that demonstrate how difficulties with basic concepts can hinder meaningful learning in upper level courses [2]. However, evidence from this study corroborates previous studies that demonstrate how difficulties with basic concepts can hinder meaningful learning in upper level courses [2].…”

Section: Introductionsupporting

confidence: 89%

Probing Student Reasoning and Intuitions in Intermediate Mechanics: An Example With Linear Oscillations

Ambrose

2007

AIP Conference Proceedings

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The study of linear oscillations-including simple harmonic, damped, and driven oscillations-is not only fundamental in classical mechanics but lies at the heart of numerous applications in the engineering sciences. Results from research conducted in the context of junior-level mechanics courses suggest the presence of specific conceptual and reasoning difficulties, many of which seem to be based on fundamental concepts. Evidence from pretests (ungraded quizzes) will be presented to illustrate critical difficulties in understanding conceptual underpinnings, relating concepts to graphical representations {e.g., motion graphs), and connecting the physics to the relevant differential equations of motion. Preliminary results from the development of a tutorial approach to instruction, modeled after Tutorials in Introductory Physics by McDermott, et al,[1] suggest that such an approach can be effective in both physics and engineering courses. (Supported by NSF grants DUE-0441426 and DUE-0442388.).

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Section: Introductionsupporting

confidence: 89%

Probing Student Reasoning and Intuitions in Intermediate Mechanics: An Example With Linear Oscillations

Ambrose

2007

AIP Conference Proceedings

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“…Sumner, Gralen & Eriksson-Quensel, 1938;McLaren, Sheppard & Wagman, 1948). -Enzymic-activity studies (Hofstee, 1949), sedimentation and activity studies (Kuff, Hogeboom & Striebich, 1955), molecular-weight estimations (Setlow, 1952) and kinetic experiments (Kistiakowsky & Lumry, 1949;Ambrose, Kistiakowsky & Kridl, 1950) all provided results which could be interpreted to some degree by assuming that the components observed in the ultracentrifuge are aggregates of the same species. In this connexion it is pertinent that a reaction involving the readily detectable sulphydryl groups in the undenatured enzyme (Hellerman, Ohinard & Dietz, 1943) to form disulphide linkages has been discussed .…”

mentioning

confidence: 99%

Evidence for the chemical interaction of urease in solution

Creeth

Nichol

1960

Biochemical Journal

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2. The percentage of lecithin in the non-ruminant 'ghosts' was over three times as high as that found in ruminant 'ghosts'. 3. In contrast, the concentrations of sphingomyehn and choline plasmalogen were higher in ruminant 'ghosts' and consequently there were no significant differences between the concentrations of total choline-containing phospholipid in the various species. 4. Phosphatidylethanolamine was markedly higher in the 'ghosts' of omnivores than in 'ghosts' of herbivores. 5. Choline-containing phospholipids (mainly lecithin) accounted for over 94 % of the plasma phospholipid of all species. 6. Of the possible acidic phospholipids in erythrocyte 'ghosts' which could function as cation carriers, phosphatidylserine was present at a relatively high concentration (8-9-16 %) in all species, phosphatidylinositol varied from 1-6 % in man to 5-8 % in the goat and phosphatidic acid was below 1.5 % in all species. We are grateful to Mr F. Hills for valuable assistance.

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“…hIolecular names should be sufficiently specific to enable other investigators to obtain the same spectrum of a sample of the same designation prepared in the same way. One must be particularly careful in the use of trivial designations for large molecules : there are many possible lecithins, trypsins, polyglutamic acids (Ambrose, 1950), and deoxyribonucleic acids. A molecule and its hydrate, steric isomer, or salt may have certain properties that are very similar, but the infrared spectra are generally quite different.…”

Section: Nomenclaturementioning

confidence: 99%