Inhibition of Root Growth by Streptomycin and Reversal of the Inhibition by Manganese

Gray, Richard

doi:10.1002/j.1537-2197.1955.tb11126.x

Cited by 22 publications

(6 citation statements)

References 10 publications

(7 reference statements)

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“…bacillar were subjected to 100 ppm of streptomycin which resulted in the permanent bleaching of organism 13 . Similar bleaching effects for barley, rye, carrot tumor tissue, pine seedlings, chlorella, and cress has been reported 14 , 15 . Wheat showed no physical growth retardation up to 200 ppm 15 .…”

Section: Introductionsupporting

confidence: 82%

“…Similar bleaching effects for barley, rye, carrot tumor tissue, pine seedlings, chlorella, and cress has been reported 14 , 15 . Wheat showed no physical growth retardation up to 200 ppm 15 . Here, depending on plants the inhibitory concentrations of SRY were found to be varying with wide range of effects from outright toxicity, lateral root development inhibition, reduced plant length, and chlorosis.…”

Section: Introductionsupporting

confidence: 82%

“…Alongside, it was also suggested that SRY might be forming a chelating complex with manganese, making them unavailable to the plants. Additive, studies on relation of SRY and Mn have provided the evidence of further correlation 15 . Addition of bacterial gene responsible for aminoglycoside resistance, streptomycin phosphotransferase, makes plants resistant to SRY based inhibitions which has been explored extensively in molecular biology for developing GMO plants 20 .…”

Section: Introductionmentioning

confidence: 96%

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Probing the effects of streptomycin on Brassica napus germination and assessing its molecular interactions using extensive molecular dynamics (MD) simulations

Patel,

Prajapati,

Goswami

et al. 2023

Sci Rep

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Antibiotics are chemical compounds that are used to treat and prevent disease in humans and animals. They have been used in animal feed for over 60 years and are widely used in industrial farming. Antibiotics can have negative environmental impacts, including the potential to contribute to the development of antibiotic-resistant organisms. They can enter the environment through various pathways, including the manufacturing process, the direct application of antibiotic-laden manure to fields, and through grazing animals. Antibiotics that are given to animals can be excreted from where they can enter soil and groundwater which enable their entry in plants. Streptomycin is an antibiotic that is used against a range of gram-positive and gram-negative bacteria, but its use has led to the development of antibiotic resistance in some pathogens. It has also been shown to have negative impacts on a range of plant species, including tobacco, tomato, and wheat. Although, the major effect of streptomycin on plant physiology have been studied, the molecular mechanisms at play are barely understood in plant body. In current study, we examined the impact of streptomycin on germination of Brassica napus and then using docking, MM-GBBSA and MD simulations identified key proteins that interact with streptomycin by performing rigorous computational screening of 106 different proteins. Our finding suggest that streptomycin might be interacting with acyl-CoA oxidases, protochlorophyllide reductase B and leucoanthocyanidin dioxygenase based on simulation and docking analysis.

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Section: Introductionsupporting

confidence: 82%

Section: Introductionsupporting

confidence: 82%

Section: Introductionmentioning

confidence: 96%

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Probing the effects of streptomycin on Brassica napus germination and assessing its molecular interactions using extensive molecular dynamics (MD) simulations

Patel,

Prajapati,

Goswami

et al. 2023

Sci Rep

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“…They suggest that manganese is important in the 02-evolving system (192). Bertrand & Wolf (193) claim that manganese is important for the utilization of citric acid in Aspergillus niger while Bromfield (194) has noted the relation between manganese deficiency in Co rynbacterium and the production of H202• Saz & SHe (195), Rosen (196), and Gray (197) observed that manganese was able to reverse the inhibitory effects of aureomycin on bacterial nitro reductase or that of streptomycin on the growth of plant tissues. Saz & Martinez (198) suggest that the relative resistance of strains of E. coli to aureomycin is closely related to their flavin and manganese requirements and that aureomycin competes with flavins for the metal.…”

Section: Other Metabolic Effectsmentioning

confidence: 96%

Minor Mineral Nutrients

Nicholas¹

1961

Annu. Rev. Plant. Physiol.

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Several well documented surveys within the last five years have covered various aspects of the trace element nutrition of plants (1 to 10). The purpose of this review is not to catalogue the work done on trace metals during the last few years but rather to attempt to show how trace metals are concerned in some of the major metabolic pathways of plant metabolism. The term plant is used here in its wider and indeed correct sense to include bacteria, fungi, algae, and higher forms, It is noteworthy that the recent work on the role of trace metals in the metabolism of higher plants was often preceded by work with microorganisms.

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“…Saz & Slie (1953), Rosen (1954) and Gray (1955) observed that manganese was able to reverse inhibitory effects of aureomycin on bacterial nitro-reductase or of streptomycin on growth of plant tissues. Saz & Slie (1953), Rosen (1954) and Gray (1955) observed that manganese was able to reverse inhibitory effects of aureomycin on bacterial nitro-reductase or of streptomycin on growth of plant tissues.…”

Section: ( I ) Beneficial Effects Under De$ciency or Toxicity Conditionsmentioning

confidence: 99%

The Metabolism of Micronutrient Elements in Plants

Hewitt

1959

Biological Reviews

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Inhibition of Root Growth by Streptomycin and Reversal of the Inhibition by Manganese

Cited by 22 publications

References 10 publications

Probing the effects of streptomycin on Brassica napus germination and assessing its molecular interactions using extensive molecular dynamics (MD) simulations

Probing the effects of streptomycin on Brassica napus germination and assessing its molecular interactions using extensive molecular dynamics (MD) simulations

Minor Mineral Nutrients

The Metabolism of Micronutrient Elements in Plants

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