Abstract:Objective: To determine the effect of rat trophoblast cell suspensions on adenosine diphosphate (ADP)-induced platelet aggregation. Materials and Methods: The trophoblasts were isolated from ectoplacental cones (a pre-placental tissue very rich in trophoblasts) developed in rat embryos on day 12 of pregnancy (normal period of gestation: 22–23 days). Platelet-rich plasma (PRP) was obtained from adult male rats. The trophoblasts were preincubated (37°C, 30 min), suspended in the medium, and then re-incubated wit… Show more
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