Inhibition of Plasma Cholinesterase and Acute Toxicity of Monocrotophos in a Neotropical Fish Prochilodus lineatus (Pisces, Curimatidae)

Croux, María Julieta Parma de; Loteste, Alicia Elena; Cazenave, Jimena

doi:10.1007/s00128-002-0070-1

Cited by 13 publications

(2 citation statements)

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“…There were mucus secretion in fish which 6 Applied and Environmental Soil Science forms a barrier between body and toxic media and thereby probably reduces contact of toxicant so as to minimize its irritating effect, or eliminates it through epidermal mucus. Similar observations were made by Rao et al [30] and Parma de Croux et al [31]. The analysis of data from the present investigation evidenced that gammalin 20 is toxic and had profound impact on behaviour and respiration in C. gariepinus in both lethal and sublethal concentrations.…”

Section: Conc (Ppb)supporting

confidence: 91%

Histopathological Effects of Gammalin 20 on African Catfish (Clarias gariepinus)

Ezemonye

Ogbomida

2010

Applied and Environmental Soil Science

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Clarias gariepinus fingerlings exposed to lethal and sublethal concentrations of Gammalin 20 were investigated in a renewal static bioassay with particular reference to behaviour, survival, and histopathological changes. Early symptoms of gammalin 20 lethal poisoning were, respiratory distress, increased physical activity, convulsions, erratic swimming, loss of equilibrium, and increased breathing activity. Behavioural response was dose dependent and decreased with decreased concentration. The 96-hour lethal concentration (LC 50 ) value was 30 ppb. Histopathological changes of the gill, liver, and intestinal tissues of fish treated with sublethal concentration of gammalin 20 for twelve weeks showed gill distortion and fusion of adjacent secondary lamella as a result of hyperplasia and excessive mucus accumulation. The liver showed swelling of hepatocytes with mild necrosis, pyknosis, and vacuolation, while the intestine showed yellow bodies of the lamina propria at the tip of the mucosal fold.

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Section: Conc (Ppb)supporting

confidence: 91%

Histopathological Effects of Gammalin 20 on African Catfish (Clarias gariepinus)

Ezemonye

Ogbomida

2010

Applied and Environmental Soil Science

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“…A number of studies are available on the inhibitory effect of MCP on acetycholine esterase (AChE) activity in different fish species (de Croux et al 2002;Rao 2004;Kavitha and Rao 2007).…”

Section: Introductionmentioning

confidence: 99%

Induction of DNA damage in the peripheral blood of zebrafish (Danio rerio) by an agricultural organophosphate pesticide, monocrotophos

et al. 2018

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The use of organophosphate pesticides (OPs) in agricultural practices in India has gained popularity due to their broad spectrum, low cost and high potency. Monocrotophos (an OP) which is a systemic and contact broad-spectrum cholinesterase inhibitor is being widely used in India. However, its use entails the damage to other non-target organisms such as fish. In the present study, zebrafish (Danio rerio) were exposed to various doses of monocrotophos (0.125, 0.625 and 1.25 lL/L) and genotoxicity studies were carried out employing the comet assay and micronucleus test in the peripheral blood of these fish after 24, 48 and 72 h of exposure. Significant DNA damage in the form of % tail DNA and micronuclei was observed in all the treated fish compared to the control. Both % tail DNA and micronuclei frequency were found to increase significantly as the concentration increased. DNA damage was also observed at all the time intervals for all treatments except in the 0.125 lL/L-treated group. A positive correlation was also observed between the comet assay and micronucleus test. The study thus suggests the use of zebrafish as an experimental model to study the genotoxic effects of agricultural pesticides using the comet assay and micronucleus test.

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Biomarker responses and morphological effects in juvenile tilapia Oreochromis mossambicus following sequential exposure to the organophosphate azinphos-methyl

Jordaan

Reinecke

2013

Aquatic Toxicology

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Inhibition of Plasma Cholinesterase and Acute Toxicity of Monocrotophos in a Neotropical Fish Prochilodus lineatus (Pisces, Curimatidae)

Cited by 13 publications

References 0 publications

Histopathological Effects of Gammalin 20 on African Catfish (Clarias gariepinus)

Histopathological Effects of Gammalin 20 on African Catfish (Clarias gariepinus)

Induction of DNA damage in the peripheral blood of zebrafish (Danio rerio) by an agricultural organophosphate pesticide, monocrotophos

Biomarker responses and morphological effects in juvenile tilapia Oreochromis mossambicus following sequential exposure to the organophosphate azinphos-methyl

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