Abstract:Background and Purpose: Cardiovascular disease (CVD) affects up to half
of the patients with chronic obstructive pulmonary disease (COPD), which
exerts deleterious impact on health outcomes and survivability. Vascular
endothelial dysfunction marks the onset of cardiovascular disease. The
present study examined the effect of a potent NADPH Oxidase (NOX)
inhibitor and free-radical scavenger, apocynin, on COPD-related CVD.
Experimental Approach: Male BALB/c mice were exposed to either room air
(Sham) or cigarette… Show more
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