Inhibition of nitric oxide synthase alters light responses and dark voltage of amphibian photoreceptors

Nöll, Gottfried N.; Billek, M.; Pietruck, Christian; Schmidt, Karl F.

doi:10.1016/0028-3908(94)90042-6

Cited by 33 publications

(23 citation statements)

References 27 publications

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“…NO may be able to increase cGMP levels in the inner segments of rod photoreceptors, thereby increasing the cGMP-gated conductance of the membrane (Koch et al, 1994;Kurenny et al, 1994), which affects both the response amplitude and the response kinetics (Noll et al, 1994). In the outer segments of rod photoreceptors, NO has also been shown to increase adenosine diphosphate (ADP) ribosylation of a variety proteins, such as transducin, G protein, and other, as yet unidentified, proteins (Brü ne and Lapetina, 1990;Pozdnyakov et al, 1993).…”

Section: Functional Considerations Of Nomentioning

confidence: 99%

Neuronal nitric oxide synthase immunoreactive neurons in the mammalian retina

Kim

Chun

2000

Microsc. Res. Tech.

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Section: Functional Considerations Of Nomentioning

confidence: 99%

Neuronal nitric oxide synthase immunoreactive neurons in the mammalian retina

Kim

Chun

2000

Microsc. Res. Tech.

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“…Thus, nitrergic ganglion cells and photoreceptors have been reported in the retina of teleosts Pottek et al, 1997;Ota et al, 1999;Haamedi and Djamgoz, 2002;Gaikwad et al, 2009], amphibians [Nöll et al, 1994;Kurenni et al, 1995;Blom et al, 2009], reptiles [Blute et al, 1997], birds [Fischer and Stell, 1999;Wilson et al, 2011;Tekmen-Clark and Gleason, 2013], and mammals [Blom et al, 2012], where protoreceptor cells always lack nitrergic labeling. Furthermore, nitrergic bipolar neurons have been described in the retina of chondrichthyes [Shiells and Falk, 1992], amphibians [Nöll et al, 1994;Kurenni et al, 1995;Blom et al, 2009], and reptiles [Cao and Eldred, 2001], whereas horizontal nitrergic cells have been reported only in teleosts [Ota et al, 1999;Haamedi and Djamgoz, 2002] and reptiles [Haverkamp and Eldred, 1998;Cuenca et al, 2000].…”

Section: Retinamentioning

confidence: 99%

“…Retinal NO might modulate the neuronal communication between bipolar and ganglion cells, like the transient conversion of synaptic inhibition to excitation [Hoffpauir et al, 2006]. Amacrine cells, either NADPH-d reactive or NOSir, have been thoroughly reported in the retina of teleosts Pottek et al, 1997;Haamedi and Djamgoz, 2002], amphibians [Nöll et al, 1994;Kurenni et al, 1995;Blom et al, 2009], reptiles , birds [Fischer and Stell, 1999;Wilson et al, 2011;Tekmen-Clark and Gleason, 2013], and mammals [Vielma et al, 2012], representing a feature shared in all osteichthyes studied. Of note, holosteans, like cladistians, lack other nitrergic cells in the retina [López et al, 2016;present results].…”

Section: Retinamentioning

confidence: 99%

Pattern of Nitrergic Neuronal System Organization in the Brain of Two Holostean Fishes (Actinopterygii: Ginglymodi)

et al. 2017

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The study of the nitrergic system, formed by the networks of neurons containing the enzyme nitric oxide synthase (NOS), has been extremely useful in unraveling neuroanatomical features of the organization of the central nervous system of vertebrates. Thus, data are available for representatives of most vertebrate classes and, in particular, several studies have detailed the organization of this system in teleosts. In contrast, no information is available regarding this neurotransmission system in the brains of holosteans, an early diverged and poorly understood group of actinopterygian fishes, currently considered a sister group of teleosts that contains only 8 species. The present study provides the first detailed information on the distribution of nitrergic cell bodies and fibers in 2 holostean species of the genus Lepisosteus, the spotted gar L. oculatus and the Florida gar L. platyrhincus. NOS immunohistochemistry and the NADPH diaphorase (NADPH-d) histochemical reaction were used, and both techniques yielded identical results, with the exception of the primary olfactory and terminal nerve fibers, which only labeled for NADPH-d exclusively in L. oculatus. Double immunohistochemistry was conducted for the simultaneous detection of NOS with tyrosine hydroxylase, choline acetyltransferase, calbindin, calretinin, and serotonin to accurately establish the localization of the nitrergic neurons and fibers in the brain of holosteans, the neuroanatomy of which has been mostly neglected, and to assess possible interactions between these neuroactive substances. Distinct groups of nitrergic cells were located in subpallial areas, the basal hypothalamus, posterior tubercle, optic tectum and mesencephalic tegmentum, reticular formation, solitary tract nucleus, spinal cord, and amacrine cells in the retina. In addition, low numbers of nitrergic cells were observed in the pallium, suprachiasmatic nucleus, prethalamic and thalamic areas, torus lateralis and torus semicircularis, cerebellar and laterodorsal tegmental nuclei, and the ventral octavolateral area. Comparison of these results with those from other classes of vertebrates, and including a segmental analysis to correlate cell populations, reveals that the pattern of the nitrergic system in holosteans is very close to that in ancestral actinopterygian fishes and highlights conserved and derived traits.

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“…However, no difference in NOS expression in brain and pituitary is found between frogs adapted to white or black background [Allaerts et al, 1997a]. Lastly, NO clearly plays a role in signal transduction in retinal ganglion cells [Hirooka et al, 2000] and photoreceptors [Tsuyama et al, 1993;Kurenni et al, 1994;Noll et al, 1994] of amphibians.…”

Section: Sensory Pathwaysmentioning

confidence: 99%

Nitric Oxide Synthase and NADPH Diaphorase Distribution in the Bullfrog <i>(Rana catesbeiana)</i> CNS: Pathways and Functional Implications

Huynh¹,

Boyd²

2007

Brain Behav Evol

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The gas nitric oxide (NO) is emerging as an important regulator of normal physiology and pathophysiology in the central nervous system (CNS). The distribution of cells releasing NO is poorly understood in non-mammalian vertebrates. Nitric oxide synthase immunocytochemistry (NOS ICC) was thus used to identify neuronal cells that contain the enzyme required for NO production in the amphibian brain and spinal cord. NADPH-diaphorase (NADPHd) histochemistry was also used because the presence of NADPHd serves as a reliable indicator of nitrergic cells. Both techniques revealed stained cells in all major structures and pathways in the bullfrog brain. Staining was identified in the olfactory glomeruli, pallium and subpallium of the telencephalon; epithalamus, thalamus, preoptic area, and hypothalamus of the diencephalon; pretectal area, optic tectum, torus semicircularis, and tegmentum of the mesencephalon; all layers of the cerebellum; reticular formation; nucleus of the solitary tract, octaval nuclei, and dorsal column nuclei of the medulla; and dorsal and motor fields of the spinal cord. In general, NADPHd histochemistry provided better staining quality, especially in subpallial regions, although NOS ICC tended to detect more cells in the olfactory bulb, pallium, ventromedial thalamus, and cerebellar Purkinje cell layer. NOS ICC was also more sensitive for motor neurons and consistently labeled them in the vagus nucleus and along the length of the rostral spinal cord. Thus, nitrergic cells were ubiquitously distributed throughout the bullfrog brain and likely serve an essential regulatory function.

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Inhibition of nitric oxide synthase alters light responses and dark voltage of amphibian photoreceptors

Cited by 33 publications

References 27 publications

Neuronal nitric oxide synthase immunoreactive neurons in the mammalian retina

Neuronal nitric oxide synthase immunoreactive neurons in the mammalian retina

Pattern of Nitrergic Neuronal System Organization in the Brain of Two Holostean Fishes (Actinopterygii: Ginglymodi)

Nitric Oxide Synthase and NADPH Diaphorase Distribution in the Bullfrog <i>(Rana catesbeiana)</i> CNS: Pathways and Functional Implications

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