Inhibition of molting by cadmium in the crab Chasmagnathus granulata (Decapoda Brachyura)

Moreno, Paula A. Rodriguez; Medesani, Daniel A.; Rodríguez, Enrique

doi:10.1016/s0166-445x(03)00029-8

Cited by 45 publications

(11 citation statements)

References 18 publications

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“…Due to their poor biodegradability, easy bioaccumulation, and high toxicity, heavy metals discharged into the sea from different sources may pose serious threats to marine organisms. For example, the spore release of Ulva pertusa is inhibited by exposure to Cu, Cd, Pb, and Zn [1]; Cd arrests the molting of the estuarine crab Chasmagnathus granulata by preventing the normal peaking of the ecdysteroids needed for molting [2]; disorganization of epithelial cells is observed in the gills of Arctic charr ( Salvelinus alpinus ) after exposure to Hg (15 μg/L) for 12 h [3]; DNA damage is induced in marine bivalve mollusk ( Mytilus edulis ) by Cu exposure at a low concentration of 18 μg/L [4]; and the embryo development of Ruditapes decussatus is observed to be inhibited when the median effective concentration (EC 50 ) values are 4.2 μg/L for Hg and 9.1 μg/L for Cu [5].…”

Section: Introductionmentioning

confidence: 99%

Probabilistic ecological risk assessment of heavy metals in western Laizhou Bay, Shandong Province, China

Chi

Tian

et al. 2019

PLoS ONE

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Considering the serious land-based pollution and the weak water exchange ability of western Laizhou Bay, it is essential to conduct an ecological risk assessment of the pollutants in this area. In this study, the ecological risk caused by heavy metals deposited in the surface sediments and those resuspended in the seawater of western Laizhou Bay was evaluated using probabilistic approaches. First, the concentrations of seven heavy metals, namely As, Cd, Cr, Cu, Hg, Pb, and Zn, in the surface sediments and seawater of western Laizhou Bay were detected during the spring and autumn of 2016. The concentrations of As, Cd, Cr, Cu, and Pb were found to be at levels comparable to those in the other global coastal systems, while those of Hg and Zn were lower than those in other coastal areas. Next, an ecological risk assessment of heavy metals in the surface sediments was performed using a typical potential ecological risk index and refined by using a Monte Carlo simulation. The results suggested low risk for the heavy metals detected in the sediments of western Laizhou Bay, with the exception of Hg in September 2016, which showed a probability (0.03%) of moderate risk. Meanwhile, the aquatic ecological risk assessment of the heavy metals was performed by applying a combination of hazard quotient (HQ) and joint probability curve. While the ecological risk of Cd, Hg, and Pb was found to be acceptable, the HQs for Cr, Cu, and Zn were greater than 1, and the overall risk probability of their adverse effects was higher than 0.05, suggesting certain ecological risk. Specifically, in the case of As, the overall risk probability was lower than 0.05, suggesting that its ecological risk was acceptable, although its HQ was greater than 1. Thus, by applying the probabilistic approaches, the ecological risk of the heavy metals in western Laizhou Bay was better characterized in this study, avoiding both overestimation and underestimation of ecological risk.

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Section: Introductionmentioning

confidence: 99%

Probabilistic ecological risk assessment of heavy metals in western Laizhou Bay, Shandong Province, China

Chi

Tian

et al. 2019

PLoS ONE

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“…Cluster analysis of the affected tags reveals that the transcriptome profile elicited by the different toxicant exposures follows a recognizable pattern. Fipronil and endosulfan both function by disrupting proper function of the γ‐amino butyric acid receptor [26], whereas cadmium is a broad spectrum stressor that affects many different systems in crustaceans, including molting [27], reproductive success [28], and DNA repair mechanisms [29]. This relationship is demonstrated by the results of the hierarchical clustering (Fig.…”

Section: Discussionmentioning

confidence: 99%

Serial analysis of gene expression reveals identifiable patterns in transcriptome profiles of Palaemonetes pugio exposed to three common environmental stressors

Griffitt

Greig²,

Chandler

et al. 2007

Enviro Toxic and Chemistry

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Serial analysis of gene expression (SAGE) is a transcriptome-profiling technique that allows accurate gene expression profiles to be generated without any need for prior sequence knowledge, making it ideal for assaying toxicant-specific genetic responses in nonmodel species. We used SAGE to perform a large-scale survey of the Palaemonetes pugio transcriptome under different chemical xenobiotic stresses. Four libraries were constructed from fipronil-exposed, endosulfan-exposed, and cadmium-exposed shrimp, as well as from carrier-control-exposed shrimp. A total of 37,152 tags were sequenced from the four libraries, including 13,754 unique tags. Statistical analysis revealed that 117 tags were differentially expressed significantly in at least one of the three exposures. Cluster analyses of the altered tags showed that fipronil and endosulfan elicit transcriptome profiles that are more similar to each other than either one was to cadmium. Quantitative polymerase chain reaction (QPCR) was performed on a subset of 46 differentially expressed tags, and largely confirmed the SAGE results. The tags were filtered to identify tags for which both SAGE and QPCR agreed in regard to the direction and magnitude of affect, and which were informative about the exposure experienced. A subset of 16 tags was identified that represents a putative biomarker suite that is indicative of exposures to the three toxicants.

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“…Snyder and Mulder (2001) reported that exposure of Homarus americanus larvae to the cyclodiene pesticide heptachlor can cause a delay in molting. Molt-inhibition by heavy metal cadmium has also been reported in the estuarine crab, Chasmagnathus granulata (Rodriguez Moreno et al, 2003). D 3-4 6 214.5 Ϯ 77.9 a, b, f 60 * Data sharing a common letter are significantly different from each other.…”

Section: Introductionmentioning

confidence: 87%

Impacts of Xenobiotics on Crustacean Molting: The Invisible Endocrine Disruption

Zou¹

2005

Integrative and Comparative Biology

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Aquatic pollution has led to the accumulation of various xenobiotics in crustaceans. A number of these environmental chemicals have been found to interfere with molting of crustaceans. Results of initial mechanistic studies with Uca pugilator suggest that the disruption of molting results from the disturbance to the Y-organ-ecdysteroid receptor (EcR) axis by xenobiotics. Such disturbance to the Y-organ-EcR axis can be caused by interference with epidermal ecdysteroid signaling and/or alterations in ecdysteroidogenesis and/or ecdysteroid disposition. Because the adverse impacts on crustacean molting cannot be readily seen in the wild, the disruption of molting represents an invisible form of endocrine disruption.

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Inhibition of molting by cadmium in the crab Chasmagnathus granulata (Decapoda Brachyura)

Cited by 45 publications

References 18 publications

Probabilistic ecological risk assessment of heavy metals in western Laizhou Bay, Shandong Province, China

Probabilistic ecological risk assessment of heavy metals in western Laizhou Bay, Shandong Province, China

Serial analysis of gene expression reveals identifiable patterns in transcriptome profiles of Palaemonetes pugio exposed to three common environmental stressors

Impacts of Xenobiotics on Crustacean Molting: The Invisible Endocrine Disruption

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