Inhibition of ischemia/reperfusion induced plasma leakage by α-tocopherol, trolox, and a shark cartilage preparation with anti-oxidant properties

Induction of inflammatory cytokines by cartilage extracts

“…While the initial interest in shark cartilage related to its alleged anticancer properties [6][7][8][9][10][11], recently, the interest is on the effect of shark cartilage on oxidative stress [12,13], the expression of adhesion molecules and fibrinolytic enzymes [14,15], and on immune function [16][17][18]. For these studies, shark cartilage has been purified preparations rather than commercial preparations of shark cartilage that are taken as oral supplements by consumers for therapeutic and/or prophylactic purposes.…”