Inhibition of in vitro metabolic activation of carcinogens by wheat sprout extracts

Lai, Chiu-Nan; Dabney, Betty J.; Shaw, Charles R.

doi:10.1080/01635587809513598

Cited by 29 publications

(14 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…194294) studied various aspects of cereal grasses related to nutrition and growth and found that highquality cereal grasses were obtained in specific soils and their nutritional profile varied with the stage of growth of the grasses. Chlorophyll is the major component of wheatgrass and responsible for inhibiting the metabolic activation of carcinogens (Lai et al, 1978;Lai, 1979). The therapeutic benefits of wheatgrass are numerous; it is therefore becoming extremely popular as nutraceutical.…”

Section: Introductionmentioning

confidence: 99%

“…Wheatgrass acts as a de-toxificant, stimulates metabolism and reduces acidity of the blood. Chlorophyll is the major component of wheatgrass and responsible for inhibiting the metabolic activation of carcinogens (Lai et al, 1978;Lai, 1979). Wheatgrass juice has been reported to decrease requirement of medications for blood and bone marrow building during chemotherapy in breast cancer patients who took wheatgrass juice (Bar-Sela et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chemical, nutritional and phenolic composition of wheatgrass and pulse shoots

Ghumman

Singh

Kaur

2017

Int J of Food Sci Tech

View full text Add to dashboard Cite

Summary Chemical, nutritional and antiradical properties of juice and shoot powder from wheatgrass and pulses were evaluated. Wheatgrass powder (WP) showed higher radical scavenging capacity, ash and chlorophyll content and lower protein content as compared to pulse powder (PP). Wheatgrass (WJP) juice powder had significantly higher K and Mg content as compared to pulse juice powder (PJP). Powders with relatively higher K and Mg content had higher radical scavenging capacity and chlorophyll content. Vanillic acid was present only in free form in both WP and PP. Luteolin was equally distributed in acid‐ and base‐bound form; sinapic acid was higher in base‐bound fraction; and protocatechuic acid was higher in acid‐bound form in both the sources. Positive correlations were found between radical scavenging capacity and ferulic acid and sinapic acid, whereas radical scavenging capacity was negatively correlated with gallic acid and p‐coumaric acid. WJP had higher glutamic acid, histidine, threonine, citrulline, arginine, gamma‐amino butyric acid (GABA) and leucine as compared to PJP. The present study highlights the nutritional benefits of wheatgrass juice.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chemical, nutritional and phenolic composition of wheatgrass and pulse shoots

Ghumman

Singh

Kaur

2017

Int J of Food Sci Tech

View full text Add to dashboard Cite

show abstract

“…Their ability to inhibit oxidative DNA damage was also demonstrated (Falcioni et al, 2002). Chlorophyll, one of the active components in the wheatgrass extract, was found to be responsible for inhibiting the metabolic activation of carcinogens (Lai et al, 1978;Lai, 1979). Recently, some clinical trials have indicated the healing properties of wheatgrass in different diseases.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the antioxidant activity of wheatgrass (Triticum aestivum L.) as a function of growth under different conditions

Kulkarni

Tilak

Acharya

et al. 2006

Phytotherapy Research

118

View full text Add to dashboard Cite

The antioxidant activity of wheatgrass, which is consumed as a dietary supplement, was estimated at different levels. The methods employed include FRAP (ferric reducing antioxidant power), ABTS (2,2'-azobis-3-ethylbenzthiazoline-6-sulfonic acid) and DPPH (1,1'-diphenyl-2-picrylhydrazyl) assays. Aqueous and ethanol extracts of wheatgrass grown under different conditions over a period of 6, 7, 8, 10 and 15 days were used. Lipid peroxidation and oxygen radical absorbance capacity (ORAC) were determined and utilized to check the potency of a few selected extracts. Different conditions used for growth were (1) tap water, (2) tap water with nutrients, (3) soil and tap water, and (4) soil with nutrients. For comparison, a commercially available wheatgrass tablet was analysed. To explain the reasons behind the observed differences, the total phenolic and flavonoid contents of the extracts were measured. These contents increased with growth under all the conditions. The ethanol extracts were found to have a higher phenolic and flavonoid content than the aqueous extracts. The highest FRAP values occurred on day 15 of growth under condition 4, the values being 0.463 and 0.573 mmol of ascorbic acid and Trolox equivalents/100 g fresh wheatgrass for aqueous and ethanol extracts, respectively. In the aqueous extracts no specific trend was observed with the DPPH assay for the different conditions nor for the growth period. In the case of ethanol extracts, however, it increased with the growth period and the wheatgrass grown in condition 4 was found to be the most effective. These extracts were also found to inhibit significantly ascorbate-Fe2+ induced lipid peroxidation in rat liver mitochondria. The ORAC values of aqueous and ethanol extracts of day 10 with condition 4 were found to be 39.9 and 48.2, respectively, being higher than those reported for many natural extracts or vegetables.

show abstract

“…Human consumption of wheat grass and other cereal grasses has increased dramatically in the last ten years, but most people have no idea of what cereal grass really is. body 3,4,5 . Wheatgrass juice reduces transfusion requirement in patients with thalassemia 6 , it is used in the treatment of active distal ulcerative colitis 7 and also inhibits DNA Oxidative damage 8 .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2014

IJPSR

View full text Add to dashboard Cite

ABSTRACT:The plant selected for the activity is obtained from the ninth day young leaves of Triticum aestivum Linn. belonging to the family Poaceae. The plant is commonly known as Wheatgrass which is used for various medicinal and health benefits for many years. It is considered as a cleansing and purifying agent from ancient times and yet can be used for its healing properties because of its nutritional values. The leaves contain many chemical compositions such as proteins, flavonoids, alkaloids, glycosides, terpenoides, saponins, fibers, tannins and phenolic compounds. Wheat grass is also rich in chlorophyll which consists of Chlorophyllin (derivatives of chlorophyll) and posses bacteriostatic and antioxidant properties. The concentrated methanolic extract showed significant hepatoprotective effect at 500 mg/kg dose in carbon tetra chloride (CCl 4 ) treated rats. The blood samples were collected and the serum was estimated for biochemical parameters SGOT, SGPT, Alkaline Phosphatase, Total and Direct Bilirubin content. The studies indicated that the recovery of liver from CCl 4 damage after the treatment was significant.

show abstract

Inhibition of in vitro metabolic activation of carcinogens by wheat sprout extracts

Cited by 29 publications

References 19 publications

Chemical, nutritional and phenolic composition of wheatgrass and pulse shoots

Chemical, nutritional and phenolic composition of wheatgrass and pulse shoots

Evaluation of the antioxidant activity of wheatgrass (Triticum aestivum L.) as a function of growth under different conditions

Untitled

Contact Info

Product

Resources

About