Inhibition of human papillomavirus type 16 gene expression by nordihydroguaiaretic acid plant lignan derivatives

Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications

“…NDGA derivatives did not affect the expression of reporter genes driven by the adenovirus major late promoter and the cytomegalovirus promoter [61]. It is predicted that the antiviral activity of NDGA derivatives is selective, depending on the virus types.…”

“…Recently, it has been reported that several methylated derivatives of NDGA possessed an inhibitory activity on the expression of reporter genes driven by some viral promoters of herpes simplex virus, human papillomavirus and human immunodeficiency virus, which was resulting from the inhibitory effect on the binding of cellular transcription factor Sp-1 to viral gene promoters [61]. NDGA derivatives did not affect the expression of reporter genes driven by the adenovirus major late promoter and the cytomegalovirus promoter [61].…”

Ailanthoidol Derivatives and their Anti-inflammatory Effects

“…1 While there have been no reports on this compound's biological activities, extracts of the bark and leaves of this tree have been used in folk medicine. The 2-arylbenzo[b]furan structures in natural and unnatural sources showed a wide variety of biological activities including anticancer, 2 antiproliferative, 3 antiinflammatory, 4 antiviral, 5 antifungal, 6 immunosuppressive, 7 antiplatelet, 8 antioxidative, 9 antifeedent, 10 and insecticidal activities. 11 The investigation of structure-activity relationships for 2-arylbenzo[b]furan substituents is still attractive due to a variety of biological activities.…”

Facile Preparation of 2-Arylbenzo[b]furan Molecules and Their Anti-inflammatory Effects

“…1 Many 2-arylbenzo[b]furan derivatives are well-known to exhibit broad range of biological activities including anticancer, 2 antiproliferative, 3 anti-inflammatory, 4 antiviral, 5 antifungal, 6 immunosuppressive, 7 antiplatelet, 8 antioxidative, 9 antifeedent, 10 and insecticidal activities. 11 The investigation of structure-activity relationships for 2-arylbenzo[b]furan substituents is still attractive due to variety of biological activities.…”