Inhibition of colonization of the chicken alimentary tract with <i>Salmonella typhimurium</i> gram-negative facultatively anaerobic bacteria

Barrow, Paul; Tucker, J. F.; Simpson, J. M.

doi:10.1017/s0950268800062063

Cited by 89 publications

(84 citation statements)

References 16 publications

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“…The reasons for this finding are not known. One explanation may be a more prolonged or a higher degree of colonization of the caeca of chickens by S. heidelberg and subsequent prevention of colonization by other salmonella serovars that are antigenically closely related [38]. Other possible explanations are a higher degree of egg shell penetration by S. heidelberg resulting in a higher percentage of day-old chicks and subsequently a higher percentage of hens that are infected with this serovar, or perhaps a higher degree of extraintestinal infection or transovarian transmission by S. heidelberg in chickens [14].…”

Section: Discussionmentioning

confidence: 99%

The prevalence of Salmonella enteritidis and other Salmonella spp. among Canadian registered commercial layer flocks

Poppe¹,

Irwin²,

Forsberg³

et al. 1991

Epidemiol. Infect.

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SUMMARYA survey was conducted to estimate the prevalence of Salmonella enteritidis and other salmonellas among Canadian commercial egg producing flocks. Environmental (faecal and eggbelt) samples from 152 of 295 (52-9 %) randomly selected flocks were contaminated with salmonellas. Thirty-five different salmonella serovars were isolated. Eggbelt samples were more often contaminated with salmonellas than faecal samples (25-7 v. 10-1 %). The most prevalent serovars were S. heidelberg, S. infantis, S. hadar, and S. schwarzengrund; they were isolated from samples of 59/295 (20%), 18/295 (6-1 %), 17/295 (5-8%), and 15/295 (541%) flocks, respectively. Feed samples of 21/295 (7-2 %) flocks were contaminated with salmonellas. Salmonella enteritidis was isolated from the environmental samples of 8/295 (2-7 %) flocks. Salmonella enteritidis phage type (PT) 8 was isolated from 5 flocks, PT 13a from 2 flocks, and PT 13 from 1 flock.

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Section: Discussionmentioning

confidence: 99%

The prevalence of Salmonella enteritidis and other Salmonella spp. among Canadian registered commercial layer flocks

Poppe¹,

Irwin²,

Forsberg³

et al. 1991

Epidemiol. Infect.

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“…For intestinal colonization studies, mutants were used which were resistant to nalidixic acid. The Nal R resistance determinant has previously been shown not to adversely affect growth, virulence or colonization (Barrow et al, 1987c;Zhang-Barber et al, 1997). Lodge et al (1992) Growth media and conditions used.…”

Section: Methodsmentioning

confidence: 99%

Glycogen production by different Salmonella enterica serotypes: contribution of functional glgC to virulence, intestinal colonization and environmental survival

McMeechan

Lovell²,

Cogan

et al. 2005

Microbiology

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In enteric bacteria, the contribution of endogenous energy sources to survival both inside and outside the host is poorly understood. The contribution of glycogen production to the virulence, colonization and environmental survival of different Salmonella enterica serotypes was assessed. Of 19 serotypes (339 strains) tested for glycogen production, 17 (256 strains) were positive. The avian-specific serovars S. Gallinarum (62 strains) and S. Pullorum (21 strains) did not produce glycogen. The sequence of glgC in three S. Gallinarum strains tested revealed an identical deletion of 11 consecutive bases, which was not present in S. Pullorum, and a CCC insertion after position 597. Transduction of S. Gallinarum and S. Pullorum to a glycogen-positive phenotype did not change the ability to colonize the intestine or affect virulence in the chicken. Mortality rates in chickens following oral infection with a S. Typhimurium glycogen mutant (glgC : : km) were not significantly reduced, although colonization of the intestine was reduced over the first 4 weeks of the trial. Growth and yield of the glgC : : km mutant were comparable to the parent. The glgC mutant survived less well in faeces and in water at 4 6C when the strain was grown in LB broth containing 0?5 % glucose, and in saline it died off more rapidly after 7 days. The data suggest that glycogen has a complex but comparatively minor role in virulence and colonization, but a more significant role in survival.

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“…Spontaneous nalidixic acid-resistant (Nalr) mutants of S. typhimurium phage type 14 1978;Impey, Mead & George, 1983;Barrow & Tucker, 1986;Barrow, Tucker & Simpson, 1987) and of S. pullorum strain 3, S.…”

Section: Salmonella Strainsmentioning

confidence: 99%

Further observations on the effect of feeding diets containing avoparcin on the excretion of salmonellas by experimentally infected chickens

Barrow

1989

Epidemiol. Infect.

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SUMMARYChickens which had been inoculated orally with a nalidixic acid-resistant strain of Salmonella typhimurium were reared on a diet containing different concentrations of avoparcin in an attempt to explain the variation in response to commercial levels of this antibiotic oberved by different workers. In one experiment small increases in faecal excretion of the inoculated salmonella occurred at 2-5 and 50 mg kg-1, with greater increases between 7-5 and 20 mg kg-'. In a second experiment there was a significant increase in excretion at 7-5 mg kg-1 and in a third experiment in which generally higher excretion rates were detected in all groups, significant increases were observed at 10 and 12-5 mg kg-1 only. In addition avoparcin significantly increased the faecal excretion of S. cholerae-suis, S. dublin and S. arizonae, serotypes not usually associated with poultry-derived food-poisoning in the United Kingdom. It did not increase faecal excretion of S. pullorum. Avoparcin at 10 mg kg-1 appeared to have little effect on the normal intestinal flora of S. typhimurium infected chickens despite the fact that when tested in vitro individual organisms were susceptible to this drug concentration. At 100 mg kg-' viable counts of intestinal enterococci and Gramnegative anaerobic bacteria were considerably reduced while those of S. typhimurium and Escherichia coli increased. Antibiotic activity due to avoparcin was detectable in the alimentary tract and there was some increase in concentration of the antibiotic in the more distal regions.

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Inhibition of colonization of the chicken alimentary tract with Salmonella typhimurium gram-negative facultatively anaerobic bacteria

Cited by 89 publications

References 16 publications

The prevalence of Salmonella enteritidis and other Salmonella spp. among Canadian registered commercial layer flocks

The prevalence of Salmonella enteritidis and other Salmonella spp. among Canadian registered commercial layer flocks

Glycogen production by different Salmonella enterica serotypes: contribution of functional glgC to virulence, intestinal colonization and environmental survival

Further observations on the effect of feeding diets containing avoparcin on the excretion of salmonellas by experimentally infected chickens

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