Inhibition of aldolase by palladium

Liu, Tsan Z.; Bhatnagar, Rajendra S.

doi:10.1007/bf01608144

Cited by 3 publications

(1 citation statement)

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“…Actually, the biological effects and biocompatibility of titania‐based compound or micro/nanoparticles have been broadly investigated in the past decade, which has also been summarized and discussed in some excellent reviews . Therefore, this review herein focuses more on the biocompatibility and biosafety of some rationally designed novel titania‐based nanoplatforms with unique responsiveness to exogenous physical irradiations.…”

Section: Biocompatibility and Biosafety Of Theranostic Titaniamentioning

confidence: 99%

Exogenous Physical Irradiation on Titania Semiconductors: Materials Chemistry and Tumor‐Specific Nanomedicine

2018

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Titania semiconductors can be activated by external physical triggers to produce electrons (e−) and holes (h+) pairs from the energy‐band structure and subsequently induce the generation of reactive oxygen species for killing cancer cells, but the traditional ultraviolet light with potential phototoxicity and low‐tissue‐penetrating depth as the irradiation source significantly hinders the further in vivo broad biomedical applications. Here, the very‐recent development of novel exogenous physical irradiation of titania semiconductors for tumor‐specific therapies based on their unique physiochemical properties, including near infrared (NIR)‐triggered photothermal hyperthermia and photodynamic therapy, X‐ray/Cerenkov radiation‐activated deep‐seated photodynamic therapy, ultrasound‐triggered sonodynamic therapy, and the intriguing synergistic therapeutic paradigms by combined exogenous physical irradiations are in focus. Most of these promising therapeutic modalities are based on the semiconductor nature of titania nanoplatforms, together with their defect modulation for photothermal hyperthermia. The biocompatibility and biosafety of these titania semiconductors are also highlighted for guaranteeing their further clinical translation. Challenges and future developments of titania‐based therapeutic nanoplatforms and the corresponding developed therapeutic modalities for potential clinical translation of tumor‐specific therapy are also discussed and outlooked.

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Section: Biocompatibility and Biosafety Of Theranostic Titaniamentioning

confidence: 99%