Inhibition of advanced glycation end products by Punica granatum Linn. leaves and its antioxidant activity

Unlocking the therapeutic treasure of pomegranate leaf: A comprehensive review on phytochemical compounds, health benefits, and future prospects

“…AGEs are pivotal in the progression of diabetic complications. Methanolic PGLE has been identified as an effective AGE inhibitor, reducing oxidative protein damage and maintaining protein thiol groups (S. N. Mestry et al, 2018 ). This anti-glycation effect, coupled with the reduction of fasting blood glucose and AGEs, underscores PGLE's role in delaying diabetic complications (S. N. Mestry & Juvekar, 2017 ).…”

“…Pomegranate leaves (PGL) have garnered significant attention for their diverse biochemical properties and health benefits (Table S2). Recent studies highlight their antioxidant capabilities, which contribute to reducing oxidative stress in various body systems ( Haseeb et al, 2017 ; S. Mestry et al, 2020 ; S. N. Mestry et al, 2018 ). Anti-inflammatory properties have been observed, particularly in reducing inflammation-related markers, offering potential therapeutic uses in inflammatory diseases ( Gheith & El-Mahmoudy, 2017 ).…”