Inheritance patterns in metabolism and growth in diallel crosses of Arabidopsis thaliana from a single growth habitat

Cubillos, Andrés Eduardo Rodríguez; Tong, Hao; Alseekh, Saleh; Lima, Francisco de Abreu e; Yu, Jing; Fernie, Alisdair R.; Nikoloski, Zoran; Laitinen, Roosa A. E.

doi:10.1038/s41437-017-0030-5

Cited by 9 publications

(3 citation statements)

References 40 publications

(50 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Notably, a small number of metabolites had non-additive values in both reciprocal hybrids (5.09–9.09% in MB and 4.77–8.01% in BM) (Fig. S 5 C), in sharp contrast to the large fractions reported previously [ 51 , 57 ]. The high MPH of metabolites identified in this study (Fig.…”

Section: Discussioncontrasting

confidence: 50%

Combined transcriptome and metabolome analysis reveals the effects of light quality on maize hybrids

et al. 2023

View full text Add to dashboard Cite

Background Heterosis, or hybrid vigor, refers to the phenotypic superiority of an F1 hybrid relative to its parents in terms of growth rate, biomass production, grain yield, and stress tolerance. Light is an energy source and main environmental cue with marked impacts on heterosis in plants. Research into the production applications and mechanism of heterosis has been conducted for over a century and a half, but little is known about the effect of light on plant heterosis. Results In this study, an integrated transcriptome and metabolome analysis was performed using maize (Zea mays L.) inbred parents, B73 and Mo17, and their hybrids, B73 × Mo17 (BM) and Mo17 × B73 (MB), grown in darkness or under far-red, red, or blue light. Most differentially expressed genes (73.72–92.50%) and differentially accumulated metabolites (84.74–94.32%) exhibited non-additive effects in BM and MB hybrids. Gene Ontology analysis revealed that differential genes and metabolites were involved in glutathione transfer, carbohydrate transport, terpenoid biosynthesis, and photosynthesis. The darkness, far-red, red, and blue light treatments were all associated with phenylpropanoid–flavonoid biosynthesis by Weighted Gene Co-expression Network Analysis and Kyoto Encyclopedia of Genes and Genomes enrichment analysis. Five genes and seven metabolites related to phenylpropanoid–flavonoid biosynthesis pathway were identified as potential contributors to the interactions between maize heterosis and light conditions. Consistent with the strong mid-parent heterosis observed for metabolites, significant increases in both fresh and dry weights were found in the MB and BM hybrids compared with their inbred parents. Unexpectedly, increasing light intensity resulted in higher biomass heterosis in MB, but lower biomass heterosis in BM. Conclusions The transcriptomic and metabolomic results provide unique insights into the effects of light quality on gene expression patterns and genotype–environment interactions, and have implications for gene mining of heterotic loci to improve maize production.

show abstract

Section: Discussioncontrasting

confidence: 50%

Combined transcriptome and metabolome analysis reveals the effects of light quality on maize hybrids

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Notably, a small number of metabolites had non-additive values in both reciprocal hybrids (5.09-9.09% in MB and 4.77-8.01% in BM) (Fig. S5C), in sharp contrast to the large fractions reported previously [50,55]. The high MPH of metabolites identi ed in this study (Fig.…”

Section: Non-additivity Of Genes and Metabolites Contributes To Maize...contrasting

confidence: 38%

Combined transcriptome and metabolome analysis reveals the effects of light quality on maize hybrids

Zhan

Guo

Cui

et al. 2022

Preprint

View full text Add to dashboard Cite

Background Heterosis, or hybrid vigor, refers to the phenotypic superiority of an F1 hybrid relative to its parents in terms of growth rate, biomass production, grain yield, and stress tolerance. Light is an energy source and main environmental cue with marked impacts on heterosis in plants. Research into the production applications and mechanism of heterosis has been conducted for over a century and a half, but little is known about the effect of light on plant heterosis. Results In this study, an integrated transcriptome and metabolome analysis was performed using maize (Zea mays L.) inbred parents, B73 and Mo17, and their hybrids, B73×Mo17 (BM) and Mo17×B73 (MB), grown in darkness or under far-red, red, or blue light. Most differentially expressed genes (73.72–92.50%) and differentially accumulated metabolites (84.74–94.32%) exhibited non-additive effects in BM and MB hybrids. Gene Ontology analysis revealed that differential genes and metabolites were involved in glutathione transfer, carbohydrate transport, terpenoid biosynthesis, and photosynthesis. The darkness, far-red, red, and blue light treatments were all associated with phenylpropanoid–flavonoid biosynthesis by Weighted Gene Co-expression Network Analysis and Kyoto Encyclopedia of Genes and Genomes enrichment analysis. Five genes and seven metabolites related to phenylpropanoid–flavonoid biosynthesis pathway were identified as potential contributors to the interactions between maize heterosis and light conditions. Consistent with the strong mid-parent heterosis observed for metabolites, significant increases in both fresh and dry weights were found in the MB and BM hybrids compared with their inbred parents. Unexpectedly, increasing light intensity resulted in higher biomass heterosis in MB, but lower biomass heterosis in BM. Conclusions Together, the transcriptomic and metabolomic results provide unique insights into the effects of light quality on gene expression patterns and genotype–environment interactions, and have implications for gene mining of heterotic loci to improve maize production.

show abstract

“…The inheritance of phenotypic traits can be additive or non-additive 50 . If the inheritance of genes indicates an additive effect, the hybrid phenotype will tend to reflect the average effect of the parent genes or midparent value (MPV) 50,51 . Phenotypic traits which deviate from the MPV in hybrid progeny are assumed to be inherited in a non-additive manor 45,50 , and inheritance can be attributed to dominant or epistatic gene effects 52 .…”

Section: Discussionmentioning

confidence: 99%

Complex Patterns of Cannabinoid Alkyl Side-Chain Inheritance in Cannabis

Welling

Лю

Raymond

et al. 2019

Sci Rep

View full text Add to dashboard Cite

The cannabinoid alkyl side-chain represents an important pharmacophore, where genetic targeting of alkyl homologs has the potential to provide enhanced forms of Cannabis for biopharmaceutical manufacture. Delta(9)-tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA) synthase genes govern dicyclic (CBDA) and tricyclic (THCA) cannabinoid composition. However, the inheritance of alkyl side-chain length has not been resolved, and few studies have investigated the contributions and interactions between cannabinoid synthesis pathway loci. To examine the inheritance of chemical phenotype (chemotype), THCAS and CBDAS genotypes were scored and alkyl cannabinoid segregation analysed in 210 F 2 progeny derived from a cross between two Cannabis chemotypes divergent for alkyl and cyclic cannabinoids. Inheritance patterns of F 2 progeny were non-Gaussian and deviated from Mendelian expectations. However, discrete alkyl cannabinoid segregation patterns consistent with digenic as well as epistatic modes of inheritance were observed among F 2 THCAS and CBDAS genotypes. These results suggest linkage between cannabinoid pathway loci and highlight the need for further detailed characterisation of cannabinoid inheritance to facilitate metabolic engineering of chemically elite germplasm.

show abstract

Inheritance patterns in metabolism and growth in diallel crosses of Arabidopsis thaliana from a single growth habitat

Cited by 9 publications

References 40 publications

Combined transcriptome and metabolome analysis reveals the effects of light quality on maize hybrids

Combined transcriptome and metabolome analysis reveals the effects of light quality on maize hybrids

Combined transcriptome and metabolome analysis reveals the effects of light quality on maize hybrids

Complex Patterns of Cannabinoid Alkyl Side-Chain Inheritance in Cannabis

Contact Info

Product

Resources

About