Inheritance and susceptibility to dental caries: A community-based study

Abstract

A BSTRACT Background: Effects of consanguineous marriage on human population are known. However, the inherited susceptibility to dental caries is unfortunately quite limited. Aim: This study aimed to assess the dental caries status (DMFT/deft [decayed-missed-filling teeth/decayed-extracted-filled teeth] index) in children born out of consanguineous and non-consanguineous marriages. Design: Household survey using a cross-sectional study design was planned, with a sample size of 2000 comprising (1600 non-consanguineous and 400 consanguineous) children, aged 6–9 years. Household survey was also planned using a systematic random sampling. Researcher conducted the study by visiting every 10th household of every 10th ward of Aligarh city, Uttar Pradesh, India. Information of risk factors for dental caries (sociodemographic, birth order, oral hygiene, feeding practices) was recorded on a pretested questionnaire with clinical examination of DMFT/deft index. Analysis: Student t test for equality of means and multivariate logistic regression were used. Results: By Student t test for equality of means, D component ( P = 0.003), d component ( P < 0.001), and deft score ( P < 0.001) were statistically significant in the consanguineous group. Multivariate logistic regression did not deduce any association of either of the study groups, but a significant association of risk factors with dental caries was observed. Conclusion: Dental caries that has multifactorial etiology, both environment and genetic factors, had an influence on the causation of dental caries in this study.

Misconceptions about Oral Health and Dentistry: Attitude of Clients at Yazd Dental School in 2023

“…However, it should be noted that dental caries is an infectious and multifactorial disease caused by the interaction between microorganisms, the host, and time. Evidence in support of hereditary predisposition to dental caries is quite sporadic (45).…”

Binary Response Analysis Using Logistic Regression in Dentistry

“…Logistic regression can be applied to investigate related factors, e.g., studies on factors related to tooth loss, tooth wear, implant failure, or temporomandibular joint clicking [ 29 – 32 ]. It can also be used to establish associations between different variables, e.g., between malocclusion and quality of life, between dentist characteristics and treatment decision, between demographic data and awareness of dental waste management, or between consanguineous marriage and dental carries [ 33 – 36 ]. Logistic regression can be used for developing a predictive model, such as sex identification using oral measurements in forensic science or the prediction of esthetic preference using demographic data [ 20 , 37 , 38 ].…”