Abstract:Inhaled steroids are potent anti-inflammatory agents used in the treatment of asthma. One of the most important side-effects of their use is their capacity to suppress the hypothalamic-pituitary-adrenal ( ) axis. Our study evaluated whether inhaled beclomethasone dipropionate (BDP) for a long period (1 month) at a dose >600 yttg/mq/day could suppress the axis and cortisol excretion. We analyzed the 24-hour urinary free cortisol excre¬ tion in 14 children (7 boys and 7 girls) receiving inhaled BDP for 1 month, … Show more
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