Inhaled morphine for palliation of dyspnea in end-stage cystic fibrosis

Abstract

Inhaled morphine was effective in relieving dyspnea in a patient with end-stage CF lung disease.

Palliative drug treatments for breathlessness in cystic fibrosis

“…Opiates and inhaled anaesthetic agents decrease the perceptual responses and thus lessen the intensity of respiratory sensation (Hayes 2010;Jennings 2002). The exact mechanism by which opioids alleviate breathlessness is still not known.…”

“…The review found that there is lack of studies discussing palliative drug treatments for breathlessness in people with CF. The available literature is in the form of case studies, which need to be assessed when making clinical decisions (Cohen 2002;Gra 2004;Hayes 2010;Janahi 2000). The excluded study was cross-over in design and compared hydrocodone to placebo (Browning 1988).…”

Counseling Children With Cystic Fibrosis: Recommendations for Practice and Counselor Self-Care

“…The later stages of CF are inundated with frequent hospitalizations. Treatment during end-stage CF is palliative rather than curative (Lowton & Gabe, 2003), and without lung transplantation, CF remains a fatal disease due to respiratory failure (Hayes, Anstead, Warner, Kuhn, & Ballard, 2010). Nevertheless, medical breakthroughs have increased the survival rate of children with CF (Blum, 1992) and now many children are living into adulthood.…”