V. Gemou-Engesaeth, A. Bush, A. B. Kay, Q. Hamid, C. J. Corrigan
Abstract:Compared with controls, children with symptomatic asthma have higher percentages of activated peripheral blood T cells synthesising cytokines believed to regulate bronchial mucosal eosinophilic inflammation. Clinical improvement with increased inhaled GC therapy is associated with reduced T cell activation and cytokine mRNA expression.
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