volume 99, issue 5, P695-703 1997
DOI: 10.1542/peds.99.5.695
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V. Gemou-Engesaeth, A. Bush, A. B. Kay, Q. Hamid, C. J. Corrigan

Abstract: Compared with controls, children with symptomatic asthma have higher percentages of activated peripheral blood T cells synthesising cytokines believed to regulate bronchial mucosal eosinophilic inflammation. Clinical improvement with increased inhaled GC therapy is associated with reduced T cell activation and cytokine mRNA expression.