Cochrane Database of Systematic Reviews 2015
DOI: 10.1002/14651858.cd011600
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Inhaled corticosteroids with combination inhaled long-acting beta2-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease

Abstract: Inhaled corticosteroids with combination inhaled long-acting beta 2 -agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease.

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“…For patients experiencing further exacerbations on dual bronchodilator therapy, outcomes may be improved with escalation to triple therapy (combining a LAMA, LABA, and inhaled corticosteroid [ICS]) [21][22][23][24]. However, available data on the optimal use of triple therapy and comparative outcomes for patients receiving dual or triple therapy are too limited for clear recommendations to be made [25][26][27].…”
Section: Introductionmentioning
confidence: 99%
“…For patients experiencing further exacerbations on dual bronchodilator therapy, outcomes may be improved with escalation to triple therapy (combining a LAMA, LABA, and inhaled corticosteroid [ICS]) [21][22][23][24]. However, available data on the optimal use of triple therapy and comparative outcomes for patients receiving dual or triple therapy are too limited for clear recommendations to be made [25][26][27].…”
Section: Introductionmentioning
confidence: 99%