Inhalation of Vapor with Medication (Diclofenac Sodium, Menthol, Methyl Salicylate and N-Acetyl Cysteine) Reduces Oxygen Need and Hospital Stay in COVID-19 Patients – A Case Control Study

Sarker, HN

doi:10.18535/jmscr/v9i6.44

jmscr

2021

DOI: 10.18535/jmscr/v9i6.44

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Inhalation of Vapor with Medication (Diclofenac Sodium, Menthol, Methyl Salicylate and N-Acetyl Cysteine) Reduces Oxygen Need and Hospital Stay in COVID-19 Patients – A Case Control Study

HN Sarker¹

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Theoretical effectiveness of steam inhalation against SARS-CoV-2 infection: updates on clinical trials, mechanism of actions, and traditional approaches

Chowdhury

Alif

Alam

et al. 2022

Heliyon

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Steam inhalation therapy can be a contemporary approach for COVID-19 affected patients of all age groups to manage respiratory conditions, though it presently lacks the scientific backing to establish itself as a befitting practice. The age of COVID-19 has facilitated this traditional home remedy to resurface among the general mass as a helpful approach for the prevention and adjuvant treatment of the disease. In this review, the means of SARS-CoV-2 infection and impact of the parameters, namely steam inhalation and heat on such infection has been delineated via enumerating the effect of the parameters in the human body and against SARS-CoV-2. The literature search was conducted using PubMed, Web of Science, Scopus, ScienceDirect, Wiley Online Library, Google Scholar, and CNKI Scholar databases. The keywords used in the survey include ‘Steam inhalation’, ‘SARS-CoV-2’, ‘COVID-19’, ‘Clinical study’, ‘Mechanism of action’, ‘Traditional uses’, ‘Phytochemistry’ and ‘Adverse effects’. Clinical studies concerning steam inhalation by COVID-19 patients have been comprehended to demarcate the scientific obscurity of the practice. The safety profile of the procedure has also been outlined emphasizing evading measures against COVID-19 and other related disease states. To recapitulate, application of the steam inhalation with herbal concoctions and phytochemicals having folkloric prevalence as an inhalable remedy against respiratory illnesses has been explored in this review work to focus on a new aspect in the COVID-19 treatment paradigm using steam and progress of further research hither.

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Theoretical effectiveness of steam inhalation against SARS-CoV-2 infection: updates on clinical trials, mechanism of actions, and traditional approaches

Chowdhury

Alif

Alam

et al. 2022

Heliyon

View full text Add to dashboard Cite

show abstract

Ayurveda-based phytochemical composition attenuates lung inflammation and precipitates pharmacokinetic interaction with favipiravir: an in vivo investigation using disease-state of acute lung injury

Gour

Dogra

Verma

et al. 2022

Natural Product Research

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Acute respiratory distress syndrome (ARDS) is the critical form of acute lung injury (ALI). Here, we investigated the effect of a defined combination of ten pure phytochemicals in equal proportions of weight (NPM) from plants, recommended by Ayurveda for any protective action against lipopolysaccharide (LPS)-induced ALI. Results indicated that NPM markedly improved protein and neutrophil contents, myeloperoxidase and hydroxyproline levels, oxidative stress markers (reduced glutathione and malonaldehyde), inflammatory cytokines and genes (IL-6, TNF-α, TGF-β and NF-κB/IκBα) in BALF/lung tissue. Results of histopathological examination of lung indicated shielding effect of NPM against ALI. NPM basically exhibited a protective effect on the lung by reducing oxidative stress and inhibiting inflammation. Although a substantial drop in oral exposure of favipiravir was observed in ALI-state, NPM treatment caused considerable augmentation in favipiravir's plasma level compared to normal-state. Overall, results offer potential insight into Ayurvedic recommendations for immunity boosters for rational use during ALI situations.

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Inhalation of Vapor with Medication (Diclofenac Sodium, Menthol, Methyl Salicylate and N-Acetyl Cysteine) Reduces Oxygen Need and Hospital Stay in COVID-19 Patients – A Case Control Study

Cited by 2 publications

References 0 publications

Theoretical effectiveness of steam inhalation against SARS-CoV-2 infection: updates on clinical trials, mechanism of actions, and traditional approaches

Theoretical effectiveness of steam inhalation against SARS-CoV-2 infection: updates on clinical trials, mechanism of actions, and traditional approaches

Ayurveda-based phytochemical composition attenuates lung inflammation and precipitates pharmacokinetic interaction with favipiravir: an in vivo investigation using disease-state of acute lung injury

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