Ingwavuma Virus (Simbu Group) from Culex and Mansonia Mosquitoes (Diptera: Culicidae) in Indonesia22

Converse, James D.; Tan, Ratna; Rachman, I.; Lee, Vernon H.; Shope, Robert E.

doi:10.1093/jmedent/22.3.339

Cited by 12 publications

(11 citation statements)

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“…Numerous other Aedes species are present in Indonesia and many are capable of transmitting the causative agents of rift valley fever and filariasis [13][14][15][16][17][18][19][20]. Furthermore, species of the genus Culex are ubiquitous throughout much of Indonesia, with many identified as the vectors of filarial parasites, as well as a number of lesser known arboviruses [19,[21][22][23][24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Characterization of vector communities and biting behavior in South Sulawesi with host decoy traps and human landing catches

et al. 2020

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Background: Indonesia has high mosquito diversity, with circulating malaria and arboviruses. Human landing catches (HLC) are ethically questionable where arboviral transmission occurs. The host decoy trap (HDT) is an exposure-free alternative outdoor sampling device. To determine HDT efficacy for local culicids, and to characterize local mosquito fauna, the trapping efficacy of the HDT was compared to that of HLCs in one peri-urban (Lakkang) and one rural (Pucak) village in Sulawesi, Indonesia. Results: In Lakkang the outdoor HLCs collected significantly more Anopheles per night (n = 22 ± 9) than the HDT (n = 3 ± 1), while the HDT collected a significantly greater nightly average of Culex mosquitoes (n = 110 ± 42), than the outdoor HLC (n = 15.1 ± 6.0). In Pucak, there was no significant difference in Anopheles collected between trap types; however, the HDT collected significantly more Culex mosquitoes than the outdoor HLC nightly average (n = 53 ± 11 vs 14 ± 3). Significantly higher proportions of blood-fed mosquitoes were found in outdoor HLC (n = 15 ± 2%) compared to HDT (n = 2 ± 0%). More blood-fed culicines were collected with outdoor HLC compared to the HDT, while Anopheles blood-fed proportions did not differ. For the HDT, 52.6%, 36.8% and 10.5% of identified blood meals were on cow, human, and dog, respectively. Identified blood meals for outdoor HLCs were 91.9% human, 6.3% cow, and 0.9% each dog and cat. Mosquitoes from Pucak were tested for arboviruses, with one Culex pool and one Armigeres pool positive for flavivirus, and one Anopheles pool positive for alphavirus. Conclusions: The HDT collected the highest abundance of culicine specimens. Outdoor HLCs collected the highest abundance of Anopheles specimens. Although the HDT can attract a range of different Asian mosquito genera and species, it remains to be optimized for Anopheles in Asia. The high proportion of human blood meals in mosquitoes collected by outdoor HLCs raises concerns on the potential exposure risk to collectors using this methodology and highlights the importance of continuing to optimize a host-mimic trap such as the HDT.

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Section: Introductionmentioning

confidence: 99%

Characterization of vector communities and biting behavior in South Sulawesi with host decoy traps and human landing catches

et al. 2020

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“…Ingwavuma virus (INGV) is a member of the Manzanilla subgroup of the Simbu serogroup and has been found in Africa, Indonesia and Asia. Infections with INGV have not yet been associated with clinical disease (26,27,28,29). Shuni virus of the Simbu group has been associated with neurological disease in horses (30).…”

Section: Fig 1 Representative Phylogenetic Organisation Of Bunyavirusesmentioning

confidence: 99%

“…INGV has been isolated from birds, pigs and Culex species mosquitoes from Thailand, Indonesia, India and Africa (27,28,29). There is also serological evidence of INGV infection of water buffalo, goats and sheep in Indonesia and Java (26). The clinical significance of INGV is not known.…”

Section: Epidemiologymentioning

confidence: 99%

“…Culicoides are considered the primary vectors of OROV (25). The transmission of INGV has not been clearly demonstrated but it has been isolated from the Culex species and thus is presumably mosquito borne (26,27,28,29). Shuni virus has been isolated from Culicoides spp.…”

Section: Transmissionmentioning

confidence: 99%

“…The Ngari virus is a genetic reassortment of Bunyamwera and Batai viruses and has been associated with severe febrile illness in humans (22,24). Although other members of the Simbu serogroup are associated with clinical disease in animals and/or humans, there is no clear clinical description for INGV infection (26,27,28,29).…”

Section: Clinical Signsmentioning

confidence: 99%

See 2 more Smart Citations

Lesser-known bunyavirus infections

Wilson¹,

Gaudreault²,

Hossain³

et al. 2015

Rev. Sci. Tech. OIE

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This paper reviews less well-known or less widely distributed viruses of the Bunyaviridae family that are nonetheless of significant veterinary and public health concern. These include: Cache Valley fever, Main Drain, Ingwavuma, Bhanja and Heartland viruses. A description of the agents, clinical signs of infection, epidemiology, and insect transmission is provided for each, and the authors discuss current diagnostic strategies plus the lack of control measures.

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Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection

et al. 2002

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A virus, named Oya virus, was isolated in Vero cell cultures from the lungs of a pig suspected of Nipah virus infection. The virus was revealed as a spherical enveloped RNA virus with a diameter of 79 nm. For identification of Oya virus, RT-PCR was performed. A common primer set for S-RNA of the Simbu serogroup of the genus Bunyavirus was able to amplify a cDNA from Oya virus RNA. The sequence data of the product revealed that the partial gene of Oya virus S-RNA segment had 65-70% homology with published cDNA sequences of Simbu serogroup viruses. The phylogenetic analysis of the data showed that the Oya virus is grouped in Simbu serogroup, but is genetically distinct from the serogroup viruses that have been analyzed molecularly. Serological surveys revealed that the virus distributed widely and densely in Malaysia.

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Ingwavuma Virus (Simbu Group) from Culex and Mansonia Mosquitoes (Diptera: Culicidae) in Indonesia22

Cited by 12 publications

References 0 publications

Characterization of vector communities and biting behavior in South Sulawesi with host decoy traps and human landing catches

Characterization of vector communities and biting behavior in South Sulawesi with host decoy traps and human landing catches

Lesser-known bunyavirus infections

Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection

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