Inguinal node dissection for melanoma in the era of sentinel lymph node biopsy

Sabel, Michael S.; Griffith, Kent A.; Arora, Alisha; Shargorodsky, Josef; Blazer, Dan G.; Rees, Riley S.; Wong, Sandra L.; Cimmino, Vincent M.; Chang, Alfred E.

doi:10.1016/j.surg.2006.12.018

Cited by 108 publications

(66 citation statements)

References 21 publications

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“…2,4,[7][8][9][10][11][12][13] In addition, whereas previous studies on wound complications include any use of therapeutic antibiotics in the criteria for defining wound infections, ACS NSQIP uses the strict CDC definitions for surgical-site infections, which do not include the administration of therapeutic antibiotics alone as a definition of wound infection. [2][3][4][6][7][8][9][10][11]13,14 A review of the literature identified seven previous studies that reported risk factors for development of wound complications after ILND for melanoma ( Table 3). The current study found a BMI of 30 or greater to be associated significantly with wound complications after ILND for cutaneous melanoma.…”

Section: Discussionmentioning

confidence: 99%

Wound Complications After Inguinal Lymph Node Dissection for Melanoma: is ACS NSQIP Adequate?

Seaberg

Greenblatt

Rettammel

et al. 2012

Journal of Surgical Research

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Background-In the treatment of melanoma, inguinal lymph node dissection (ILND) is the standard of care for palpable or biopsy-proven lymph node metastases. Wound complications occur frequently after ILND. In the current study, the multicenter American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) was utilized to examine the frequency and predictors of wound complications after ILND.

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Section: Discussionmentioning

confidence: 99%

Wound Complications After Inguinal Lymph Node Dissection for Melanoma: is ACS NSQIP Adequate?

Seaberg

Greenblatt

Rettammel

et al. 2012

Journal of Surgical Research

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“…[2][3][4][5][6][7][8] Therefore, the goal of the current study was to perform a systematic review of health-related quality of life (HRQOL) studies in patients with lower extremity lymphedema in order to summarize the known literature on the effects of lymphedema. In addition, we aimed to use validated standards including the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) 9 and check lists such the Efficace criteria 10 (Table 1) to assess the validity of these studies, identify potential biases, and define high quality measures.…”

Section: Lymphatic Research and Biologymentioning

confidence: 99%

Systematic Review of Quality of Life and Patient Reported Outcomes in Patients with Oncologic Related Lower Extremity Lymphedema

Cemal

Jewell

Albornoz

et al. 2013

Lymphatic Research and Biology

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Background: Lower limb lymphedema (LLL) is a common complication of cancer treatment. The disease is chronic and progressive with no cure. Although a common and significant source of morbidity, the impact of this condition on health-related quality of life (HRQOL) has only recently been addressed. In effort to identify valid treatment strategies for LLL, we performed a systematic review, identifying studies describing HRQOL outcomes in patients with LLL secondary to cancer. Methods and Results: Seven medical databases were searched to identify reports using validated Patient Reported Outcome (PRO) instruments on patients with cancer-related LLL. Studies were classified by levels of evidence set by the Agency for Healthcare Research and Quality (AHRQ) and evaluated using the Efficace criteria. 25 studies were identified, 6 met inclusion criteria. Levels of evidence included: no level I studies, level II (n = 3), level III (n = 1), and level 4 (n = 2). 50% of studies were compliant with the Efficace criteria. 5 PRO HRQOL instruments were used, but only 1 was specific to cancer-related lymphedema. Treatment strategies assessed included complete decongestive physiotherapy (CDP), exercise, and compression bandaging. CDP yielded significant enhancements in HRQOL. Conclusions: There is a deficit in high quality studies for HRQOL in patients with LLL secondary to cancer. Furthermore, of the studies present, most did not conform to guidelines set for assessment of HRQOL, nor did they use lymphedema condition specific PRO instruments. New measures specific to assessing LLL are necessary to gain more accurate evaluation of how this debilitating disorder affects HRQOL.

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“…Inguinal as opposed to axillary LND may be associated with particularly high morbidity. Sabel and colleagues reported on 212 patients who underwent inguinal LND and observed a rate of wound complications of 19% and lymphedema of 30%, both of which were significantly higher in patients with clinically positive nodes than those with microscopic nodal disease [Sabel et al, 2007]. Chang and colleagues recently reported the results of a prospective study of 53 patients undergoing inguinal LND, and they observed an overall 30-day wound complication rate of 77% [Chang et al, 2010].…”

Section: Indication For and Extent Of Lymph Node Dissectionmentioning

confidence: 99%