Ingestão De Dicromato De Potássio Induz Alterações Morfológicas Em Cardiomiócitos De Ratos

Abstract

The aim of this studywas to analyze the effects of diet’s potassium dichromate supplementation on cardiac muscle tissue morphology in rats. Forty male rats were used, divided into G0: basal diet, G1: basal diet + 12 mg.Kg-1potassium dichromate, G2: basal diet + 24 mg.Kg-1and G3: basal diet + 36 mg.Kg-1for 90 days. The animals were euthanized, with heart extraction for morphological analysis and fractal dimension analysis. Anova One-Way, Kruskall-Wallis, Tukey and Dunnwere used to compare the results, with p<0.05. There is no differences on body mass and heart mass. G1showed greater tissue inflammation of compared to G2 and G0. It was concluded that potassium dichromate generatesmorphological changes byproinflammatory effect in rat cardiomyocytes.