Ingeniería Tisular Para Regeneración Nerviosa: Una Revisión

Strategies for Guidance and Electrical and Biological Stimulation in a Neural Regeneration Device

“…SCs transplants have been tested for the regeneration of peripheral nerves, since they are capable of synthesizing and secreting neurotrophic factors and adhesion molecules to promote and guide axonal growth and remyelination (Figure 11) [97,102] . In addition, SCs secrete signaling molecules that attract macrophages, thus supporting neuronal survival and promoting axonal growth (Figure 11) [103] .…”

“…This is the reason why when dealing with a large lesion it is not enough the exclusive use of cell therapy to regenerate the injury in a satisfactory way. The most promising studies nowadays are those that combine the use of biomaterials as a guide for nerve regeneration with cell therapy [22,102] . Thus, the application of cellular and molecular therapies combined with scaffolds has increased the regenerative capacity in the nervous system [102] .…”

“…The most promising studies nowadays are those that combine the use of biomaterials as a guide for nerve regeneration with cell therapy [22,102] . Thus, the application of cellular and molecular therapies combined with scaffolds has increased the regenerative capacity in the nervous system [102] .…”