Infusions of Blood and Other Fluids via the Bone Marrow

Tocantins, Leandro M.; O’Neill, James C.; Jones, Holly

doi:10.1001/jama.1941.02820410007002

Cited by 115 publications

(37 citation statements)

References 2 publications

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“…As IBMI provides for rapid absorption and easy access, it was subsequently used to deliver blood and other fluids, specially in critically ill children and war-wounded soldiers. 4 More recently, there has been renewed interest in IBMI as a technique to minimize nonspecific cell loss when transplanting a limited number of hematopoietic progenitor cells (HPCs) and hematopoietic stem cells (HSCs), such as with umbilical cord blood (UCB) grafts. 5,6 Allogeneic hematopoietic cell transplantation (HCT) has become an accepted treatment for hematologic malignancies, hereditary immunodeficiencies and storage diseases.…”

Section: Introductionmentioning

confidence: 99%

Going straight to the point: intra-BM injection of hematopoietic progenitors

Ramírez

Wagner

Brunstein

2010

Bone Marrow Transplant

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Section: Introductionmentioning

confidence: 99%

Going straight to the point: intra-BM injection of hematopoietic progenitors

Ramírez

Wagner

Brunstein

2010

Bone Marrow Transplant

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“…In den 40er Jahren fand die intraos säre Infusionstechnik Eingang in die kli nische Praxis [9,20,54]. Rasch etablierte sie sich in der Pädiatrie zu einem Standard der Infusionstechnik [20], wurde dann je doch durch die aufkommenden Plastik verweilkatheter abgelöst und geriet wie der in Vergessenheit.…”

Section: Historischesunclassified

Intraossäre Infusion

et al. 2009

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Timely establishment of venous access in infants and toddlers can prove a particularly challenging task. Since the 1940s the technique of intraosseous infusion has established itself as a valuable alternative means for rapid, efficient and safe delivery of drugs and fluids to critically ill children. Whereas international guidelines for paediatric emergency medical care have assigned intraosseous infusion a high priority, most anaesthetists utilize this well-proven technique with great reluctance. This article describes the technique of intraosseous infusion, introduces two different cannulation systems, and discusses its potential indications in paediatric anaesthesia, based on current emergency medical care guidelines as well as some of our own case studies. In particular, children with acutely life-threatening conditions, such as circulatory arrest, laryngospasm, acute airway haemorrhage, hypovolaemic shock or hypothermia secondary to extensive burns, should receive an intraosseous cannula if intravenous access cannot be rapidly established. Future discussion may reveal whether a transiently inserted intraosseous infusion would also be indicated if the child with difficult or impossible venous access presents without acute life-threatening conditions for anaesthesia. Successful application of the intraosseous infusion technique requires immediate access to the necessary equipment, intensive education, continuous training and clear guidelines for its application in an anaesthesia department.

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“…Eine der ersten wissenschaftlichen Veröf-fentlichungen über die Anwendung eines intraossären Gefäßzugangs 99,110,111,112,113,114,115,116]. Die ersten kommerziellen IO-Kathetersysteme wurden von Tocantins und O'Neil entwickelten, Heinild beschrieb deren Anwendung bei über 1000 Kindern [50, 110,111,112,113,114,115,116].…”

Section: Geschichtlicher Rückblickunclassified

“…Die ersten kommerziellen IO-Kathetersysteme wurden von Tocantins und O'Neil entwickelten, Heinild beschrieb deren Anwendung bei über 1000 Kindern [50, 110,111,112,113,114,115,116]. Während des 2.…”

Section: Geschichtlicher Rückblickunclassified

Intraossäre Infusion beim Erwachsenen

Leidel

Kanz²,

Mutschler³

et al. 2008

Chirurg

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Intraosseous (IO) infusion methods have been common for emergency treatment in infants and children for years. The role of IO access in adults is however much less clear, but its importance in this patient group is increasing, and different devices are available today. Each device has strengths and weaknesses, but all achieve rapid vascular access even in challenging situations. The potential of IO access regarding both therapeutic and diagnostic options has been shown in several operational studies in and out of hospital. Insertion times require between 1 and 2 min in most cases, while insertion and handling of the IO access devices seem to be easy and reliable. The flow rates of IO access devices for adults are lower than those of large-bore peripheral intravenous catheters, but fluid resuscitation is possible in most cases at least with pressure bag infusion systems. Most drugs administered intravenously can be given intraosseously in equivalent dosages and with the same effects. Nevertheless the limitations and risks of IO access routes need to be considered for each application. Rapid IO access is now possible in all age groups, and the 2005 AHA Guidelines favor it over drug administration via the endotracheal tube.

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Infusions of Blood and Other Fluids via the Bone Marrow

Cited by 115 publications

References 2 publications

Going straight to the point: intra-BM injection of hematopoietic progenitors

Going straight to the point: intra-BM injection of hematopoietic progenitors

Intraossäre Infusion

Intraossäre Infusion beim Erwachsenen

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