Infundibulocystic basal cell carcinoma: dermoscopic findings and histologic correlation

Roldán–Marín, Rodrigo; Leal-Osuna, Sergio; Lammoglia-Ordiales, Lorena; Toussaint–Caire, Sonia

doi:10.5826/dpc.0403a09

Cited by 7 publications

(7 citation statements)

References 11 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cystic structures have been seen in BCCs, where they tend to be scattered throughout the anastomosing basaloid tumor islands. A controversial infundibulocystic variant has been described, accounting for less than 5% of all BCCs [7][8][9][10][11][12]. It is more common in basal cell nevoid syndrome and results from a mutation in the Hedgehog pathway [13].…”

Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma With Unusual Benign-Appearing Cystic Features on Histology

Asad¹,

Alkul²,

Shimizu³

et al. 2023

Cureus

View full text Add to dashboard Cite

Squamous cell carcinoma (SCC) is a malignancy that arises from keratinocytes of the epidermis. Cystic variants of several types of cutaneous neoplasms have been rarely described in the literature. We report a case of biopsy-proven, well-differentiated invasive SCC treated with Mohs surgery. On frozen sections, the pathology slides showed benign-appearing cystic structures in the margins that persisted after it had appeared that the original malignancy had been cleared. After taking another Mohs stage due to clinical suspicion, additional SCC was found and was subsequently cleared after two more Mohs stages. To the best of our knowledge, this is the first report to histologically demonstrate biopsy-proven invasive SCC with benign-appearing cystic structures on frozen sections.

show abstract

Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma With Unusual Benign-Appearing Cystic Features on Histology

Asad¹,

Alkul²,

Shimizu³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…Most mixed-type BCCs have a common nodular component, which might have an association with the stem cells of the hair follicles (Peterson et al, 2015). By analysing dermoscopic and histopathological correlates, clear evidence comes to light -the aggressive potential of tumour does not increase only by enlargement of neoplasm (Roldán-Marín et al, 2014;Emiroglu et al, 2015;Enache et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

What We Need to Learn When Exploring the Mixed Basal Cell Carcinoma of Head and Neck

Moisejenko-Goluboviča

Volkovs

Иванова

et al. 2021

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

View full text Add to dashboard Cite

Coexistence of different histopathological types of basal cell carcinomas (BCC) in the same anatomical localisation is rare, and, therefore, is engaging for histopathologists and clinicians. In many cases, the determination of a neoplasm type remains difficult, since BCC may consist of more than one histopathological subtype. Mixed BCCs often present with an aggressive course and recurrence when compared to other subtypes of a tumour. Furthermore, tumours of this type are associated with time-consuming treatment and not a very satisfactory cosmetic result, thus worsening the quality of the patient’s life. Several clinical studies have been published regarding the histopathologically diverse tumours developed in the same anatomical region; however, largely peculiarities of mixed BCCs are not explored sufficiently. The purpose of this study was to substantiate the use of dermoscopy and morphology, assessing mixed type BCC of the head and neck. The tumours were removed with a surgical excision of 1 cm margins, and the tumour sites were assessed in a 24-month-long follow-up period. The dermoscopic characteristics of mixed and aggressive BCC are analysed in this study. Finally, to better estimate the invading cone of the tumour, a complex morphology, which included collagen type IV and podoplanin immunohistochemistry, and electron microscopy were used.

show abstract

“…Short fine telangiectasias are due to dilated blood vessels in papillary dermis. [9] Maple leaf like structures are due to multifocal tumour nests containing pigment aggregates, connecting to each other as well as to the epidermis with lobular extension. They are located in papillary dermis and sometimes in reticular dermis.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological and dermoscopic features in a case of linear and unilateral basaloid follicular hamartoma

Muhammed

Dongre

Khopkar

2019

Indian Dermatol Online J

View full text Add to dashboard Cite

Linear and unilateral basaloid follicular hamartoma (BFH) is a rare disease that manifests with papules and plaques with distribution along lines of Blaschko. It runs a benign course but with the risk of basal cell carcinoma (BCC) in long term course. BCC can be differentiated from BFH with histopathology and immunohistochemistry. Dermoscopic features of BCC are well studied. Dermoscopic features of BFH are not yet described in literature in detail probably due to rarity of the disease. Here, we present a case of extensive linear and unilateral BFH with its clinicohistopathological and dermoscopic features. The lesions were extensive to involve scalp, face, neck, upper, and lower trunk. Dermoscopy revealed features similar to that of BCC including brown-grey globules and dots, in focus dots, brown linear and arciform structures, crown vessels, short fine telangiectasias, spoke wheel like structures without central dark point, white structureless areas with telangiectasias and keratotic plug. Other dermoscopic features of BCC like arborizing vessels, blue-grey ovoid nests, maple leaf-like areas, concentric structures, ulcerations, erosions and white streaks were absent in this case.

show abstract

Infundibulocystic basal cell carcinoma: dermoscopic findings and histologic correlation

Cited by 7 publications

References 11 publications

Squamous Cell Carcinoma With Unusual Benign-Appearing Cystic Features on Histology

Squamous Cell Carcinoma With Unusual Benign-Appearing Cystic Features on Histology

What We Need to Learn When Exploring the Mixed Basal Cell Carcinoma of Head and Neck

Clinicopathological and dermoscopic features in a case of linear and unilateral basaloid follicular hamartoma

Contact Info

Product

Resources

About