Infrared Transmission Characteristics and Laser Tissue Interaction of Albino Pigskin Using Pulsed NIR Laser Light

Abbas, Hisham A.; Triplett, Gregory

doi:10.1155/2013/451208

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Tissue transmission associated attenuation coefficient was the highest for 660 nm, minimal for 830 nm and the least for 904 nm [22]. Optical transmission of controllable infrared source parameters demonstrates maximum efficiencies of 86% [23] with higher duty cycles transmitting greater power over shorter exposure times while lower duty cycles transmit higher power at lower temperatures. Variations in efficiency of transmission indicate that the power transmission percentage can be appropriately tuned.…”

Section: Introductionmentioning

confidence: 97%

Higher pulse frequency of near-infrared laser irradiation increases penetration depth for novel biomedical applications

et al. 2021

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Background The clinical efficiency of laser treatments is limited by the low penetration of visible light used in certain procedures like photodynamic therapy (PDT). Second Harmonic Generation (SHG) PDT is an innovative technique to overcome this limitation that enables the use of Near Infrared (NIR) light instead of visible light. NIR frequency bands present an optical window for deeper penetration into biological tissue. In this research, we compare the penetration depths of 405 and 808 nm continuous wave (CW) lasers and 808 nm pulsed wave (PW) laser in two different modes (high and low frequency). Methods Increasing thicknesses of beef and chicken tissue samples were irradiated under CW and PW lasers to determine penetration depths. Results The 808 nm CW laser penetrates 2.3 and 2.4 times deeper than the 405 nm CW laser in beef and chicken samples, respectively. 808 nm PW (pulse frequency—500 Hz) penetrates deeper than CW laser at the same wavelength. Further, increasing the pulse frequency achieves higher penetration depths. High frequency 808 nm PW (pulse frequency—71.4 MHz) penetrates 7.4- and 6.0-times deeper than 405 nm CW laser in chicken and beef, respectively. Conclusions The results demonstrate the higher penetration depths of high frequency PW laser compared to low frequency PW laser, CW laser of the same wavelength and CW laser with half the wavelength. The results indicate that integrating SHG in the PDT process along with pulsed NIR light may allow the treatment of 6–7 times bigger tumours than conventional PDT using blue light.

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Section: Introductionmentioning

confidence: 97%

Higher pulse frequency of near-infrared laser irradiation increases penetration depth for novel biomedical applications

et al. 2021

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Thermal Analysis of Infrared Irradiation-Assisted Nanosecond-Pulsed Tumor Ablation

Hornef

Edelblute

Schoenbach

et al. 2020

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nanosecond pulsed electric fields (nspef) have the potential to treat a variety of cancer types including melanoma, pancreatic and lung squamous cancers. Recent studies show that nsPEF-based cancer therapy may be improved further with the assistance of moderate heating of the target. A feedbacklooped heating system, utilizing a 980-nm fiber optic laser, was integrated into nsPEF electrodes for tumor ablation. The laser beam profile was determined to be Gaussian using a knife-edge technique. Thermal properties of the biological target were evaluated based on the treatment area, penetration depth and thermal distribution due to laser irradiation with or without nsPEF. Synergistic effects between nsPEF and the moderately elevated temperature at the target was observed, resulting in enhanced overall survival tumor regression up to 50% in the treatment of lung squamous cell cancer in mice.

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Infrared Transmission Characteristics and Laser Tissue Interaction of Albino Pigskin Using Pulsed NIR Laser Light

Cited by 2 publications

References 9 publications

Higher pulse frequency of near-infrared laser irradiation increases penetration depth for novel biomedical applications

Higher pulse frequency of near-infrared laser irradiation increases penetration depth for novel biomedical applications

Thermal Analysis of Infrared Irradiation-Assisted Nanosecond-Pulsed Tumor Ablation

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