Infrared Spectrometric Determination of Deuterium Oxide in Water

Thornton, V.; Condon, F. E.

doi:10.1021/ac60041a021

Cited by 71 publications

(17 citation statements)

References 14 publications

(2 reference statements)

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“…After a 1-3 h equilibration period, urine samples were collected. The urine samples were then placed in a distillation apparatus, and HOD concentrations were determined by infrared absorption (THORNTON and CONDON, 1950;TRENNER et al, 1953;TURNER et al, 1960;JONES and MACKENZIE, 1960;STANSELL and MOJICA,1968;KOMIYA et al,1981). The error of deuterium concentration determined by this method is 2.55% (KOMIYA et al, 1981).…”

Section: Methodsmentioning

confidence: 99%

Age-Related Changes in Body Fat Distribution in Middle-Aged and Elderly Japanese.

Komiya

Muraoka

Zhang

et al. 1992

Journal of Anthropological Society of Nippon

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Total body fat mass was estimated in a group of 65 healthy male and 39 healthy female Japanese aged 40-77 using the D2O dilution method , and by measurement of skinfold thickness at 14 sites. The weights of skin, and subcutaneous and internal adipose tissue were calculated. The women had a higher total adipose tissue weight than the men (p<0.01). Absolute subcutaneous adipose tissue weight in women was about double that in men. However, absolute internal adipose tissue weight and internal adipose tissue weight as a percentage of body weight showed no significant sex difference.The relationship of total and subcutaneous adipose tissue weight with age showed a correlation of r = -0.283 (p <0.05) and r = -0.367 (p<0.01), respectively, for men and r = -0.329 (p< 0.05) and r = -0.428 (p< 0.01), respectively, for women. The correlation of internal adipose tissue weight with age was not significant, but the internal adipose tissue weight/total adipose tissue weight ratio increased steadily with age in both sexes.

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Section: Methodsmentioning

confidence: 99%

Age-Related Changes in Body Fat Distribution in Middle-Aged and Elderly Japanese.

Komiya

Muraoka

Zhang

et al. 1992

Journal of Anthropological Society of Nippon

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“…Deuterium has been analysed by infrared (IR) spectrometry as early as several decades ago (Thornton and Condon, 1950), however, we were able to reach detection limits in the lower range combined with relatively high precision through the introduction of FTIR or Fourier transform infrared technology with its associated software.…”

Section: Bomem Michelson-type Spectrometermentioning

confidence: 99%

Deuterium–hydrogen ratios, electrical conductivity and nitrate for high-resolution dating of polar ice cores

Dreschhoff¹,

Jungner²,

Laird

2020

Tellus B: Chemical and Physical Meteorology

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In order to support the very high time resolution required to observe short-term variations in nitrates and all other ions represented by electrical conductivity in polar ice, a Fourier transform infrared spectrometer was developed for measurement of deuterium concentration in ice samples, as an additional support for the timescale of ultra-high resolution. The portable instrument provided the possibility to measure deuterium concentration on exactly the same samples as used for measuring nitrate concentrations and liquid electrical conductivity, thus verifying that the original dating of the annual variations in nitrate was correct. We present basic information about how the high-resolution data were obtained and discuss their reliability and significance.

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“…Other methods for the analysis of deuterium have been investigated, including gas chromatography, elevation of freezing point and density determination, 8 but these generally lack the necessary sensitivity and have not found widespread use. Infrared spectroscopic methods [9][10][11][12][13][14][15][16][17][18][19][20][21][22] have gained greater acceptance and are now in common use for the analysis of deuterium in body composition studies. 12,13,19,20,23,24 Fourier School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia transform infrared spectroscopy (FT-IR) has become the method of choice owing to its relatively high sensitivity and simplicity of technique.…”

Section: Introductionmentioning

confidence: 99%

Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy for the Quantitative Analysis of Deuterium in Plasma: Application to Total Body Water Determination in Humans and Other Animals

Ward

2021

Appl Spectrosc

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Conventional methods for measuring the concentration of deuterium in body fluids are by either isotope ratio mass spectrometry or Fourier transformed infra-red transmission (FTIR) spectroscopy. The latter method is often preferred as it is less expensive and time consuming; however, having a lower sensitivity means a larger sample volume is required. This study investigated an alternative FTIR spectroscopic method, attenuated total reflection Fourier transformed infra-red spectroscopy (ATR-FTIR), which has the potential to provide shorter analysis times while requiring smaller sample volumes. Deuterium was assayed by ATR-FTIR in plasma in the concentration range 0.5 to 2.5 mg mL-1, typical of those observed in tracer dilution measurements of total body water. Minimal sample preparation was required and analysis time was substantially decreased compared to transmission FTIR. Samples were analysed with high precision (CV < 0.5 %). Precision of assay was maintained when assaying plasma volumes of only 10 ïL. The application of the method to the determination of total body water in humans and animals (horses) was demonstrated. A rapid and simple method for the measurement of deuterium in plasma is described that only requires very small sample volumes, rendering the method suitable for use in paediatrics where blood sampling is required to be kept to a minimum.

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Infrared Spectrometric Determination of Deuterium Oxide in Water

Cited by 71 publications

References 14 publications

Age-Related Changes in Body Fat Distribution in Middle-Aged and Elderly Japanese.

Age-Related Changes in Body Fat Distribution in Middle-Aged and Elderly Japanese.

Deuterium–hydrogen ratios, electrical conductivity and nitrate for high-resolution dating of polar ice cores

Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy for the Quantitative Analysis of Deuterium in Plasma: Application to Total Body Water Determination in Humans and Other Animals

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