Bound state rovibrational energy calculations using a high-level intermolecular potential surface are reported for H2O-CO and D2O-CO. They predict the ground K = 1 levels to lie about 20 (12) cm -1 above K = 0 for H2O-CO (D2O-CO) in good agreement with past experiments. But the first excited K = 1 levels are predicted to lie about 3 cm -1 below their K = 0 counterparts in both cases. Line strength calculations also indicate that mid-infrared transitions from the K = 0 ground state to this seemingly anomalous excited K = 1 state should be observable. These predictions are strikingly verified by new spectroscopic measurements covering the C-O stretch region around 2200 cm -1 for H2O-CO, D2O-CO, and HOD-CO, and the O-D stretch region around 2700 cm -1 for D2O-CO, HOD-CO, and DOH-CO. The experiments probe a pulsed supersonic slit jet expansion using tunable infrared quantum cascade laser or optical parametric oscillator sources. Discrete perturbations in the O-D stretch region give an experimental lower limit to the binding energy D0 of about 340 cm -1 for D2O-CO, as compared to our calculated value of 368 cm -1 . Wavefunction plots are presented to help understand the intermolecular dynamics of H2O-CO. Coriolis interactions are invoked to explain the seemingly anomalous energies of the first excited K = 1 levels.