Infrared-active quadruple contrast FePt nanoparticles for multiple scale molecular imaging

Chou, Shang Wei; Liu, Chien‐Liang; Liu, Tzu-Ming; Yu, Shaohua; Kuo, Lun Chang; Wu, Cheng Ham; Hsieh, Tsung Yuan; Wu, Pei Chun; Tsai, Ming Rung; Yang, Che Chang; Chang, Kai Yao; Lu, Meng Hua; Li, Pai Chi; Chen, Shi Ping; Wang, Yu-Hsin; Lu, Chen Wen; Chen, Yi An; Huang, Chih Chia; Wang, Churng Ren Chris; Hsiao, Jong‐Kai; Li, Meng Lin; Chou, Pi‐Tai

doi:10.1016/j.biomaterials.2016.01.053

Cited by 29 publications

(26 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, it was reported that FePt NPs could also be used as an infrared-active nanoplatform for four imaging modalities (optical/photoacoustic/CT/MRI), which may allow for multiscale imaging from the cellular level to wholebody imaging. 192 …”

Section: Strategies To Achieve High Relaxivity For Mri Contrast Enmentioning

confidence: 99%

Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

et al. 2017

View full text Add to dashboard Cite

Magnetic resonance imaging (MRI) is a highly valuable non-invasive imaging tool owing to its exquisite soft tissue contrast, high spatial resolution, lack of ionizing radiation, and wide clinical applicability. Contrast agents (CAs) can be used to further enhance the sensitivity of MRI to obtain information-rich images. Recently, extensive research efforts have been focused on the design and synthesis of high-performance inorganic nanoparticle-based CAs to improve the quality and specificity of MRI. Herein, the basic rules, including the choice of metal ions, effect of electron motion on water relaxation, and involved mechanisms, of CAs for MRI have been elucidated in detail. In particular, various design principles, including size control, surface modification (e.g. organic ligand, silica shell, and inorganic nanolayers), and shape regulation, to impact relaxation of water molecules have been discussed in detail. Comprehensive understanding of how these factors work can guide the engineering of future inorganic nanoparticles with high relaxivity. Finally, we have summarized the currently available strategies and their mechanism for obtaining high-performance CAs and discussed the challenges and future developments of nanoparticulate CAs for clinical translation in MRI.

show abstract

Section: Strategies To Achieve High Relaxivity For Mri Contrast Enmentioning

confidence: 99%

Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

et al. 2017

View full text Add to dashboard Cite

show abstract

“…In addition, the low cytotoxicity of the FePt@Fe 2 O 3 nanoparticles makes them a potential candidate for use in drug delivery. Separately, Chou et al, demonstrated the use of infrared-active FePt nanoparticles as a quadruple-contrast in multiscale molecular imaging in CT, MRI, photoacoustic imaging, and high-order multiphoton luminescence microscopy [102]. The FePt nanoparticles gave a higher photoacoustic response than gold nanorods and allowed for the visualization of in vivo targeting with four techniques at the same time, making them flexible and versatile imaging contrasts.…”

Section: Bioimagingmentioning

confidence: 99%

“…Sensing LSPR shift AuAg [163] Surface-enhanced Raman scattering (SERS) AuAg [76] AuAg [166] GMR sensor; competition assay FeCo [112,113,187] Magnetic capture FePt [171] Magnetically-enhanced colorimetric biosensing PtCo [117] QCM with magnetically controlled permeability AuCo [80] Electrochemical biosensor PtPd [96] Imaging An imaging probe screening with dual energy mammography or computed tomography AuAg [71] The optical absorption cross sections AuAg [72] MRI contrast agent (no imaging) FePt [103] MRI in vitro FePt [105] FeNi [115] PtCo [40] MRI in vivo AuCu [84] FeCo [110] FePt [177] Dual modal CT/MRI molecular imaging in vitro and in vivo FePt [132] MRI and near-infrared agents FeCo [111] Multimodal imaging − Computed tomography (CT), − Magnetic resonance imaging (MRI), − Photoacoustic (PA) imaging, − High-order multiphoton luminescence (HOMPL) microscopy FePt [102] in vivo Multimodal SERS-MRI-CT imaging AuFe [79] in vivo NIR thermal imaging and photoacoustic imaging AuPt [95] Thermal treatment in vitro hyperthermia FePt [109] Photothermal FePt [104] Hyperthermia CuNi [119,188] Tumor chemo-photothermal therapy AuPt [95]…”

Section: Application Principle Materials Referencementioning

confidence: 99%

Bimetallic Nanoparticles: Enhanced Magnetic and Optical Properties for Emerging Biological Applications

et al. 2018

View full text Add to dashboard Cite

Metal nanoparticles are extensively studied due to their unique chemical and physical properties, which differ from the properties of their respective bulk materials. Likewise, the properties of heterogeneous bimetallic structures are far more attractive than those of single-component nanoparticles. For example, the incorporation of a second metal into a nanoparticle structure influences and can potentially enhance the optical/plasmonic and magnetic properties of the material. This review focuses on the enhanced optical/plasmonic and magnetic properties offered by bimetallic nanoparticles and their corresponding impact on biological applications. In this review, we summarize the predominant structures of bimetallic nanoparticles, outline their synthesis methods, and highlight their use in biological applications, both diagnostic and therapeutic, which are dictated by their various optical/plasmonic and magnetic properties.

show abstract

“…Therefore, a distinguishable CT contrast image can only be obtained under a large dosage of iodinated compounds, which may potentially cause serious renal toxicity (Kherlopian et al, ). In the last decade, there has been substantial interest in nanoparticle‐based contrast agents for in vivo CT imaging (Chou et al, ). Gold (Z = 79) has a higher atomic number than iodine (Z = 53), and thus, a better contrast with a lower X‐ray dose can be achieved (Caltagirone, Bettoschi, Garau, & Montis, ; Singh, Patel, Leong, & Kim, 2017).…”

Section: Computed Tomographymentioning

confidence: 99%

Functional mesoporous silica nanoparticles for bio‐imaging applications

Geun

Kim

2018

WIREs Nanomed Nanobiotechnol

View full text Add to dashboard Cite

Biomedical investigations using mesoporous silica nanoparticles (MSNs) have received significant attention because of their unique properties including controllable mesoporous structure, high specific surface area, large pore volume, and tunable particle size. These unique features make MSNs suitable for simultaneous diagnosis and therapy with unique advantages to encapsulate and load a variety of therapeutic agents, deliver these agents to the desired location, and release the drugs in a controlled manner. Among various clinical areas, nanomaterials-based bio-imaging techniques have advanced rapidly with the development of diverse functional nanoparticles. Due to the unique features of MSNs, an imaging agent supported by MSNs can be a promising system for developing targeted bio-imaging contrast agents with high structural stability and enhanced functionality that enable imaging of various modalities. Here, we review the recent achievements on the development of functional MSNs for bio-imaging applications, including optical imaging, magnetic resonance imaging (MRI), positron emission tomography (PET), computed tomography (CT), ultrasound imaging, and multimodal imaging for early diagnosis. With further improvement in noninvasive bio-imaging techniques, the MSN-supported imaging agent systems are expected to contribute to clinical applications in the future. This article is categorized under: Diagnostic Tools > In vivo Nanodiagnostics and Imaging Nanotechnology Approaches to Biology > Nanoscale Systems in Biology.

show abstract

Infrared-active quadruple contrast FePt nanoparticles for multiple scale molecular imaging

Cited by 29 publications

References 46 publications

Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

Bimetallic Nanoparticles: Enhanced Magnetic and Optical Properties for Emerging Biological Applications

Functional mesoporous silica nanoparticles for bio‐imaging applications

Contact Info

Product

Resources

About