Blockchain is an evolving technology with promising applications in various sectors. The introduction of blockchain in the industry has the potential to provide a significant competitive advantage, even though it still is in the early stages of its adoption, particularly in supply chains. The implementation of blockchain technologies affects all the operational aspects of a production and supply chain system, including its sustainable performance. In these terms, there is a raising of concerns regarding the impact of the integration of blockchain on the economic viability of the organization, the total environmental footprint that results from its use, and the social matters regarding its control, safety assurance, and governance. The scope of this paper is to identify the implications of the integration of blockchain technologies in the industry concerning the three main pillars of sustainability.