The economic transformations carried out in the country are accompanied by numerous problems that lead to an increase in public discontent and to the quality of governance and the results of reforms. This is dictated by objective circumstances. Indeed, many ongoing projects, as well as the leadership they carry out, deserve low marks. However, the point is not only the low qualifications of managers of different levels or the ineffectiveness of the proposed updates. Like any open system, the economy, considered by us as a set of forward and backward connections, processes and phenomena, has a whole set of probabilistic states. Studying them and the conditions for transition to them dictates the need to develop new approaches to managing them. In the presented work, an attempt is made to develop new approaches to the management process, to assess the effectiveness of management efforts associated with reforming the economic system in order to overcome imbalances in the development of industries, regions, territories. And also to give a methodological justification for the application of the synergeticinstitutional approach in solving the tasks.