Abstract-Provision of health care and well-being services at end-user residence, together with its benefits, brings important concerns to be dealt with. This article discusses selected issues in dependable pervasive eHealth services support.Dependable services need to be implemented in a resourceefficient and safe way due to constrained and concurrent, preexisting conditions and radio environment. Security is a must when dealing with personal information, even more critical when regarding health. Once these fundamental requirements are satisfied, and services designed in an effective manner, social significance can be achieved in various scenarios. After having discussed the above viewpoints, the article concludes with the future directions in eHealth IoT including scaling the system down to the nanoscale, to interact more intimately with biological organisms.