“…Recently, the M2 proton-selective ion channel function mediates virus budding (Rossman et al, 2010b;. The M2 cytoplasmic tail also plays a role in progeny virus production and virion morphology (Chen et al, 2008;Iwatsuki-Horimoto et al 2006;McCown & Pekosz, 2005;Rossman et al, 2010a;Zhang et al, 2000). The influenza B virus BM2 protein has a proton channel activity (Mould et al, 2003), and is involved in the incorporation of the virus genome into virions (Imai et al, 2004;2008).…”