Influenza Vaccination and COVID-19 Mortality in the USA: An Ecological Study

Zanettini, Claudio; Omar, Mohamed; Dinalankara, Wikum; Imada, Eddie Luidy; Colantuoni, Elizabeth; Parmigiani, Giovanni; Marchionni, Luigi

doi:10.3390/vaccines9050427

Cited by 53 publications

(39 citation statements)

References 48 publications

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“…In addition, influenza vaccinated patients were less likely to require hospitalization (OR = 0.58), mechanical ventilation (OR = 0.45) and had a shorter hospital stay (OR = 0.76). This result leads to the conclusion that the influenza vaccine is assumed to reduce the COVID-19 disease burden [41]. By contrast, in Italy, independently, Belingeri et al and Pedote et al found no evidence of a relationship between the influenza vaccine and either a COVID-19 diagnosis or a positive SARS-CoV-2 serology test in a group of healthcare workers and COVID-19 infected patients, respectively.…”

Section: The Most Significant Findings Of the Studymentioning

confidence: 97%

The Impact of the COVID-19 Emergency on Life Activities and Delivery of Healthcare Services in the Elderly Population

Agrawal

Makuch

Dróżdż

et al. 2021

JCM

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Due to the prevailing pandemic of the coronavirus disease COVID-19, we are experiencing emotional and social isolation, which negatively affects mental and physical health, particularly among the elderly population. In this study, we performed a cross-sectional analysis based on computer-assisted telephone interviews of 500 Polish adults aged 60 years or older in order to determine the impact of the SARS-CoV-2 pandemic on the older population’s behavior, life activity, and delivery of healthcare services. According to our study, COVID-19 infection entailed a substantial change in older people’s behavior. Over 50%, nearly 80%, and more than 25% of the surveyed participants reduced their social, recreational, and professional activities, respectively. The most significant change in senior’s behavior due to the fear of COVID-19 infection was observed in patients (1) with cardiac and pulmonary problems, (2) being on multi-drug therapy, (3) vaccinated against influenza, and (4) with several mental difficulties including loneliness, social isolation, and depression. Furthermore, we demonstrated that 10% of participants canceled planned hospitalization due to the fear of COVID-19 infection. This was observed primarily in patients suffering from chronic heart and lung diseases, vaccinated against influenza, exhibiting the reluctance to carry out more complex daily activities, and with a higher level of anxiety, social loneliness, and malnutrition. Thus, these groups of seniors require more attention; hence, we propose telemedicine as a strategy directed to them that provides clinical healthcare and information regarding measurements, control, and protection against SARS-CoV-2 during the prevailing COVID-19 pandemic. We believe this strategy may improve treatment outcomes, reduce comorbidities-related complications and unnecessary hospitalizations.

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Section: The Most Significant Findings Of the Studymentioning

confidence: 97%

The Impact of the COVID-19 Emergency on Life Activities and Delivery of Healthcare Services in the Elderly Population

Agrawal

Makuch

Dróżdż

et al. 2021

JCM

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“…Specifically, they should receive vaccines against S. pneumoniae (PCV13 and PPSV23) [122]. Such vaccinations could stimulate an immune response in older adults; although the data are not fully supportive of this hypothesis, pneumococcal vaccinations could reduce the risk and potentially severe infections, including COVID-19 [123][124][125]. Thindwa et al [119] estimated COVID-19 mortality associated with pneumococcal coinfection and reported that PPSV23 in older adults could reduce potentially pneumococcal-attributable COVID-19 morbidity and mortality.…”

Section: Recommendations Of Pneumococcal Vaccine For Reducing the Ris...mentioning

confidence: 99%

Promising Expectations for Pneumococcal Vaccination during COVID-19

Ser

Sim

et al. 2021

Vaccines

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The emergence of new viral infections has increased over the decades. The novel virus is one such pathogen liable for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, popularly known as coronavirus disease 2019 (COVID-19). Most fatalities during the past century’s influenza pandemics have cooperated with bacterial co/secondary infections. Unfortunately, many reports have claimed that bacterial co-infection is also predominant in COVID-19 patients (COVID-19 associated co/secondary infection prevalence is up to 45.0%). In the COVID-19 pandemic, Streptococcus pneumoniae is the most common coinfecting pathogen. Half of the COVID-19 mortality cases showed co-infection, and pneumonia-related COVID-19 mortality in patients >65 years was 23%. The weakening of immune function caused by COVID-19 remains a high-risk factor for pneumococcal disease. Pneumococcal disease and COVID-19 also have similar risk factors. For example, underlying medical conditions on COVID-19 and pneumococcal diseases increase the risk for severe illness at any age; COVID-19 is now considered a primary risk factor for pneumococcal pneumonia and invasive pneumococcal disease. Thus, pneumococcal vaccination during the COVID-19 pandemic has become more critical than ever. This review presents positive studies of pneumococcal vaccination in patients with COVID-19 and other medical conditions and the correlational effects of pneumococcal disease with COVID-19 to prevent morbidity and mortality from co/secondary infections and superinfections. It also reports the importance and role of pneumococcal vaccination during the current COVID-19 pandemic era to strengthen the global health system.

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“…As by Fragoulis et al [62], the numbers of vaccinated individuals with ARDs have risen in the season of 2020/2021 and reached 83%. It could also be beneficial in the view of decrease of COVID-19 mortality [63].…”

Section: Vaccination and Rheumatic Pathologymentioning

confidence: 99%

COVID-19 from a rheumatology perspective: bibliometric and altmetric analysis

et al. 2021

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The Coronavirus disease 2019 (COVID-19) outbreak turned out the greatest pandemic for decades. It challenged enormously the global health system, forcing it to adjust to the new realities. We aimed to analyze articles covering COVID-19 papers in the rheumatological field and outline emerging topics raising within this frame. We applied the bibliometric database Scopus for our literature search and conducted it on the 5th of June using the following keywords: "rheumatic" OR "rheumatology" OR "rheumatoid arthritis" OR "systemic lupus erythematosus" OR "myositis" OR "systemic sclerosis" OR "vasculitis" OR "arthritis" OR "ankylosing spondylitis" AND "COVID-19". We analyzed all selected articles according to various aspects: type of document, authorship, journal, citations score, rheumatology field, country of origin, language, and keywords. With the help of the software tool VOSviewer version 1.6.15, we have built the visualizing network of authors and keywords co-occurrence. The measurement of the social impact of articles was made using Altmetric data. This study included 1430 retrieved articles with open access mostly. The top five journals in this field were Annals of the Rheumatic Diseases (n = 65), Rheumatology International (n = 51), Clinical Rheumatology (n = 50), Lancet Rheumatology (n = 50), and Frontiers In Immunology (n = 33). Most studies originate from countries with a high incidence of COVID-19 among the general population (the USA-387; Italy-268; . Original Articles (42.1%) were the most common articles' type, following by Letters (24.4%), Reviews (21.7%), Notes (6%), Editorials (4.8%), Erratum (1%). According to the citations scores, articles dedicated to the clinical course of COVID-19 in patients with rheumatic diseases were of the highest importance for the scientific rheumatologic community. Rheumatoid arthritis (n = 527), systemic lupus erythematosus (n = 393), vasculitis (n = 267), myositis (n = 71), systemic sclerosis (n = 68), and psoriatic arthritis (n = 68) were the most widely discussed rheumatic diseases in the view of COVID-19. The analysis of Altmetric and citations scores revealed a moderate correlation between them. This article provides a comprehensive bibliometric and altmetric analysis of COVID-19 related articles in the rheumatology field and summarizes data about features of rheumatology service in the time of the pandemic.

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Influenza Vaccination and COVID-19 Mortality in the USA: An Ecological Study

Cited by 53 publications

References 48 publications

The Impact of the COVID-19 Emergency on Life Activities and Delivery of Healthcare Services in the Elderly Population

The Impact of the COVID-19 Emergency on Life Activities and Delivery of Healthcare Services in the Elderly Population

Promising Expectations for Pneumococcal Vaccination during COVID-19

COVID-19 from a rheumatology perspective: bibliometric and altmetric analysis

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