Influenza outbreaks and hospital bed occupancy in Rome (Italy): current management does not accommodate for seasonal variations in demand

Fusco, Danilo; Saitto, Carlo; Arcà, Massimo; Perucci, Carlo A.

doi:10.1258/095148406775322025

Cited by 9 publications

(4 citation statements)

References 26 publications

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“…The second wave in autumn is causing increasing trends in hospital and intensive care unit admissions. 2 In the average winter season, hospital bed occupancy is higher, due to influenza patients 3,4 . In the 2020‐21 winter season with the ongoing COVID‐19 pandemic, it is crucial to reduce the burden on hospitals, as much as possible.…”

Section: Introductionmentioning

confidence: 99%

Absence of association between 2019‐20 influenza vaccination and COVID‐19: Results of the European I‐MOVE‐COVID‐19 primary care project, March‐August 2020

Kissling¹,

Hooiveld

Brytting

et al. 2021

Influenza Resp Viruses

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Background Claims of influenza vaccination increasing COVID‐19 risk are circulating. Within the I‐MOVE‐COVID‐19 primary care multicentre study, we measured the association between 2019‐20 influenza vaccination and COVID‐19. Methods We conducted a multicentre test‐negative case‐control study at primary care level, in study sites in five European countries, from March to August 2020. Patients presenting with acute respiratory infection were swabbed, with demographic, 2019‐20 influenza vaccination and clinical information documented. Using logistic regression, we measured the adjusted odds ratio (aOR), adjusting for study site and age, sex, calendar time, presence of chronic conditions. The main analysis included patients swabbed ≤7 days after onset from the three countries with <15% of missing influenza vaccination. In secondary analyses, we included five countries, using multiple imputation with chained equations to account for missing data. Results We included 257 COVID‐19 cases and 1631 controls in the main analysis (three countries). The overall aOR between influenza vaccination and COVID‐19 was 0.93 (95% CI: 0.66‐1.32). The aOR was 0.92 (95% CI: 0.58‐1.46) and 0.92 (95% CI: 0.51‐1.67) among those aged 20‐59 and ≥60 years, respectively. In secondary analyses, we included 6457 cases and 69 272 controls. The imputed aOR was 0.87 (95% CI: 0.79‐0.95) among all ages and any delay between swab and symptom onset. Conclusions There was no evidence that COVID‐19 cases were more likely to be vaccinated against influenza than controls. Influenza vaccination should be encouraged among target groups for vaccination. I‐MOVE‐COVID‐19 will continue documenting influenza vaccination status in 2020‐21, in order to learn about effects of recent influenza vaccination.

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Section: Introductionmentioning

confidence: 99%

Absence of association between 2019‐20 influenza vaccination and COVID‐19: Results of the European I‐MOVE‐COVID‐19 primary care project, March‐August 2020

Kissling¹,

Hooiveld

Brytting

et al. 2021

Influenza Resp Viruses

View full text Add to dashboard Cite

show abstract

“…First, the proposed measures are easy to implement and do not require additional economic, structural, or human resources. Moreover, the intervention was implemented in an environment of demand and usual care pressure during the study period . However, the intervention does require the determined commitment and coordination of the management team of the center and the different professional groups involved in the process.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the intervention was implemented in an environment of demand and usual care pressure during the study period. 34,35 However, the intervention does require the determined commitment and coordination of the management team of the center and the different professional groups involved in the process. A relatively simple strategy can have a great impact on patient safety.…”

Section: P-valuementioning

confidence: 99%

Real‐time surveillance systems: Applicability for the control of influenza in acute care

Quirós‐González

Rodríguez-Pérez

Haro-Pérez

et al. 2020

Influenza Resp Viruses

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Background:The high morbidity and mortality caused by influenza viruses translate into a great impact on specialized health care. Apart from the annual vaccination, the relevance of other measures to prevent and control this infection is unknown. The objective of our research was to determine the importance of a real-time surveillance system to establish early extended transmission precautions. Methods: Quasi-experimental before-and-after study comparing the influenza cases detected in hospitalized adults during the 2016/2017 season (264 patients) with those detected after the implementation of a real-time surveillance system in the 2017/2018 season (519 patients). The improvements included early microbiological diagnosis, immediate communication of results, constant updating of patient information, coordination among professionals, periodic surveillance of the adequacy of preventive measures, and greater control of roommates. The effectiveness of the intervention was determined from the nosocomial infection rate in each season.Results: After the real-time surveillance system for influenza was implemented, patients with early microbiological diagnosis and immediate isolation increased significantly (13.7% vs 68.2%; P < .001). In addition, nosocomial infections decreased from 17% to 9.2% (P = .001) and overall hospital stay was significantly reduced. Assuming that the entire effect was due to the intervention, the absolute risk reduction was 7.8% and number needed to treat was 12.8. Conclusion:The results in our study reveal the impact of nosocomial transmission of influenza virus in a tertiary hospital and highlight the need to supplement traditional strategies with novel methodologies such as modern surveillance systems based on early diagnosis, close case monitoring, and coordination among professionals. K E Y W O R D Scross-infection, influenza, microbiology, preventive medicine, vaccination

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“…2 In the average winter season, hospital bed occupancy is higher, due to influenza patients. 3,4 In the 2020-21 winter season with the ongoing COVID-19 pandemic, it is crucial to reduce the burden on hospitals, as much as possible. Influenza vaccination, despite its sometime moderate vaccine effectiveness, is an important factor in reducing hospitalisations 5 and is specifically important for the 2020-21 season with SARS-CoV-2 circulation.…”

Section: Introductionmentioning

confidence: 99%

Absence of association between 2019–20 influenza vaccination and COVID-19: results of the European I-MOVE-COVID-19 primary care project, March–August 2020

Kissling¹,

Hooiveld

Brytting

et al. 2021

Preprint

View full text Add to dashboard Cite

Background Claims of influenza vaccination increasing COVID-19 risk are circulating. Within the I-MOVE-COVID-19 primary care multicentre study, we measured the association between 2019–20 influenza vaccination and COVID-19. Methods We conducted a multicentre test-negative case-control study at primary care level, in study sites in five European countries, from March–August 2020. Patients presenting with acute respiratory infection were swabbed, with demographic, 2019–20 influenza vaccination and clinical information documented. Using logistic regression we measured the adjusted odds ratio (aOR), adjusting for study site and age, sex, calendar time, presence of chronic conditions. The main analysis included patients swabbed ≤7 days after onset from the three countries with <15% of missing influenza vaccination. In secondary analyses, we included five countries, using multiple imputation with chained equations to account for missing data. Results We included 257 COVID-19 cases and 1631 controls in the main analysis (three countries). The overall aOR between influenza vaccination and COVID-19 was 0.93 (95% CI: 0.66–1.32). The aOR was 0.92 (95% CI: 0.58–1.46) and 0.92 (95%CI: 0.51–1.67) among those aged 20–59 and ≥60 years, respectively. In secondary analyses, we included 6457 cases and 69272 controls. The imputed aOR was 0.87 (95% CI: 0.79–0.95) among all ages and any delay between swab and symptom onset. Conclusions There was no evidence that COVID-19 cases were more likely to be vaccinated against influenza than controls. Influenza vaccination should be encouraged among target groups for vaccination. I-MOVE-COVID-19 will continue documenting influenza vaccination status in 2020-21, in order to learn about effects of recent influenza vaccination.

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Influenza outbreaks and hospital bed occupancy in Rome (Italy): current management does not accommodate for seasonal variations in demand

Abstract: Hospital specialty wards react poorly and single handedly to a minor and predictable burden. Any winter bed crisis in the Lazio region is probably the result of defective management of available beds more than excess in demand.

Cited by 9 publications

References 26 publications

Absence of association between 2019‐20 influenza vaccination and COVID‐19: Results of the European I‐MOVE‐COVID‐19 primary care project, March‐August 2020

Absence of association between 2019‐20 influenza vaccination and COVID‐19: Results of the European I‐MOVE‐COVID‐19 primary care project, March‐August 2020

Real‐time surveillance systems: Applicability for the control of influenza in acute care

Absence of association between 2019–20 influenza vaccination and COVID-19: results of the European I-MOVE-COVID-19 primary care project, March–August 2020

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