Influenza-a Infection in Children

Brocklebank, J T; Court, S. D. M.; McQuillin, Joyce; Gardner, P. S.

doi:10.1016/s0140-6736(72)91902-2

Cited by 109 publications

(35 citation statements)

References 11 publications

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“…18,19 The incidence of convulsion associated with influenza A infection had been re- ported to range from 6% to 40%. [12][13][14][15] The large variation in the incidence of febrile seizure associated with influenza A seen in different studies can be partially explained by differences in age. 15 In other studies, the patient population was heavily skewed in favor of those with severe complications, including convulsions.…”

Section: Discussionmentioning

confidence: 99%

“…Thirty-one of 61 children admitted during an epidemic in Newcastle on Tyne were admitted because of convulsion. 12 Most studies were also limited by the small number of patients included. The present study represents the largest report of children with febrile seizures associated with influenza A infection in hospitalized children.…”

Section: Discussionmentioning

confidence: 99%

“…Some reports have included children with underlying causes for seizures, and their relevance to the pathogenesis of febrile seizures is limited. [12][13][14][15] In 1998, a new influenza A antigenic variant, the H3N2 Sydney virus, appeared in Hong Kong. Some pediatricians had the impression that febrile seizures associated with this new variant were more common that previously seen with influenza A.…”

mentioning

confidence: 99%

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Influenza A Infection Is an Important Cause of Febrile Seizures

et al. 2001

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ABSTRACT. Objectives. To compare the incidence of febrile seizures in children hospitalized for influenza A infection with parainfluenza and adenovirus infection and to examine the hypothesis that children hospitalized for influenza A (variant Sydney/H3N2) during the 1998 season in Hong Kong had more frequent and refractory seizures when compared with other respiratory viruses, including the A/Wuhan H3N2 variant that was present in the previous year.Methods. Medical records of children between 6 months and 5 years of age admitted for influenza A infection in 1998 were reviewed. For comparison, records of children of the same age group with influenza A infection in 1997, and with parainfluenza and adenovirus infections between 1996 and 1998 were reviewed. Children who were afebrile or who had an underlying neurologic disorder were excluded.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Influenza A Infection Is an Important Cause of Febrile Seizures

et al. 2001

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“…In the group with chronic neurologic disease, H1N1 positivity was found more frequently. When examined in terms of other chronic diseases, it was found that influenza B infection occured more frequently and the complication rate was higher in individuals with chronic lung disease, chronic heart disease or immune system problems (9,22). However, it is not known why influenza B virus leads to more serious findings in these patient groups.…”

Section: Discussionmentioning

confidence: 99%

Clinical differences of influenza subspecies among hospitalized children

Acar¹,

Sütçü²,

Aktürk³

et al. 2017

Turk Pediatri Ars

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Aim: Clinical findings, mortality, and morbidity rates differ among influenza subspecies. Awareness of these differences will lead physicians to choose the proper diagnostic and therapeutic strategies and to foresee possible complications. The aim of this study was to evaluate the clinical differences of influenza subspecies among hospitalized children. Material and Methods:Hospitalized children with proven influenza infection by polymerase chain reaction on nasopharyngeal swab specimens in our clinic, between December 2013 and March 2016, were enrolled. These children were divided into 3 groups as Influenza A/H1N1 (n=42), Influenza A/H3N2 (n=23), and Influenza B (n=35). Results:The median age of the children was 51.5 months (range, 3-204 months). The most common presenting symptoms were fever (n=83), cough (n=58), and difficulty in breathing (n=25). The most common non-respiratory findings were lymphadenopathy (n=18) and gastrointestinal system involvement (n=17). Sixty-two percent of the patients (n=62) had chronic diseases. H1N1 and H3N2 were significantly more common among patients with chronic neurologic disorders and renal failure, respectively. Leukopenia (n=32) and thrombocytopenia (n=22) were the most common pathologic laboratory findings. Neutropenia, elevated CRP levels, and antibiotic use were significantly more common among patients with H1N1 infection. Seven patients were transferred to the intensive care unit with diagnoses of acute respiratory distress syndrome (n=4), encephalitis (n=2), and bronchiolitis (n=1). Two patients with chronic diseases and H1N1 infection died secondary to acute respiratory distress syndrome.Conclusions: Influenza A/H1N1 infection represented more severe clinical disease. (Turk Pediatri Ars 2017; 52: 15-22)

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“…The rate for children aged [1][2][3][4] in Group A wards is the highest of the three age groups and, though not reaching statistical significance when compared with the rate for children under a year, is significantly higher than that for children of 5 years and over. It has been noted that children admitted to hospital with illnesses caused by influenza A infection are most commonly aged between 1 and 2 years (Brocklebank, Court, McQuillin & Gardner, 1972). This age distribution is in contrast to that for R.S.…”

mentioning

confidence: 94%