Influenza a antibodies in cervine animals

Abstract

In the haemagglutination inhibition (HI) test, 20 cervine sera, most of which came from Northern Germany, were treated with receptor destroying enzyme (RDE) and 11 sera were found to contain antibodies against the H1N1 (A/USSR 90/77) and H3N2 (A/Victoria 13/75, A/Texas 1/77) influenza viruses. Only two sera contained antibodies against H3N2 viruses, and seven sera were negative. Evidence of the specificity of influenza antibodies was provided by the following findings: 1) the IgG serum extracts showed the same inhibitory activity of haemagglutinin as the RDE treated sera; 2) addition of protein A led to an increase in the HI titers; 3) in the haemolysis in gel test, some of the HI positive sera formed haemolysis in gel test, some of the HI positive sera formed haemolysis rings of the same diameter as hyperimmune antiinfluenza A (H1N1) serum; and 4) the cervine sera reacted positively in the neuraminidase inhibition (NI) test. It is remarkable that influenza H1N1 antibodies were found in the serum of one cervine before this virus strain appeared in humans.

Single-Stranded RNA Viruses

“…Lvov when they isolated the A/Rangifer tarandus/Chukotka/1254/77 (H6N2) strain from slowed reindeer (Rangifer tarandus) in the Chukotka Peninsula. 206 The Russian State Collection of Viruses in the D.I. Ivanovsky Institute of Virology contains the strains A/ deer/Primorje/1201/78 (H1N1), isolated from red deer (Cervus elaphus) in Primorsky Krai, and A/Rangifer tarandus/Yamal/865/90 (H13N1), isolated from reindeer (R. tarandus) on the coast of the Barents Sea.…”

“…Specific antibodies towards Influenza A (H1N1) and A (H3N2) were detected in the sera of red deer (C. elaphus) and elks (Alces alces) in the north of Germany. 207,208 S.Q. Li established the presence of about a 10% immune layer toward Influenza A (H1N1) and A (H3N2) among Cervidae in the northeastern provinces of China.…”