"Influência dos bisfosfonatos na movimentação dentária induzida, na freqüência e nas dimensões das reabsorções radiculares associadas"

Abstract

As palavras são absolutamente insuficientes para meus sentimentos de gratidão a tantas pessoas que fazem diferença em minha vida. No entanto, deixo registrado meu reconhecimento e gratidão àqueles que contribuíram direta ou indiretamente com este trabalho:

The use of bisphosphonates does not contraindicate orthodontic and other types of treatment!

“…Since the first bisphosphonates and bisphosphonate-related treatments (including treatment of osteopenia related to menopause conducted to avoid osteoporosis) arose, we have microscopically investigated its effects on maxillary bone, induced tooth movement, osseointegration and root resorption. 7 , 8 , 11 , 13 …”

“…Although they have been widely used for medical purposes, bisphosphonates have caught dentists' attention in the last few years, only. 9 , 11 , 13 Nevertheless, we notice great lack of basic scientific grounds that aid clinicians to understand not only bisphosphonates mechanism of action, but also their clinical applicability, side effects, variation in presentation and dosage. Ignorance leads to myths, controversies and mystification within any knowledge domain.…”

Bisphosphonates: opinion or scientific-based restrictions?

“…Although they have been widely used for medical purposes, bisphosphonates have caught dentists' attention in the last few years, only. 9,11,13 Nevertheless, we notice great lack of basic scientiic grounds which allow better understanding not only of bisphosphonates mechanism of action, but also their clinical applicability, side bisphosphonates would be of major concern, given that bone remodeling could be afected. However, their therapeutic effects were not satisfactory as the medication remained inactive when orally taken and had rapid hydrolysis when administered via parenteral.…”

Reabsorção óssea à distância na movimentação ortodôntica: quando se inicia e o como ocorre a reorganização periodontal

“…3,10 In general, experimental times were 5 to 7 days in the first studies. 7,8,9,13 However, it remains unclear what tissue phenomena take place in murine maxillary first molar roots that received intense forces and produce indirect bone resorption. Several questions raised in previous studies 4,6,10,11 » When palatal expansion is used, appliance anchorage in maxillary premolars promotes hyalinization of the periodontal ligament on the buccal face.…”