Influencia del suplemento con inulina enriquecida con fructooligosacáridos sobre el contenido y la densidad mineral ósea tras el parto y la lactación en ratas

Abstract

I, López Pedrosa JM. Infl uencia del suplemento con inulina enriquecida con fructooligosacáridos sobre el contenido y la densidad mineral ósea tras el parto y la lactación en ratas. Nutr Hosp 2016;33:1074-1081 DOI: http://dx.doi.org/10.20960/nh.569Infl uencia del suplemento con inulina enriquecida con fructooligosacáridos sobre el contenido y la densidad mineral ósea tras el parto y la lactación en ratas AbstractIntroduction: Pregnancy and lactation are related with temporary decreases in maternal bone mineral density (BMD). Calcium supplementation could be benefi cial to prevent bone loss of maternal skeleton. Other nutrients, such as prebiotics have showed to produce an increase of the mineral absorption and therefore affecting bone mineralization. Objective: To study the effect of maternal diet supplementation with prebiotic oligofructose-enriched inulin during gestation and lactation on the maternal bone mineral content (BMC) and BMD at the end of lactation. Methods: Pregnant rats were fed with standard diet (CC group), calcium fortifi ed diet (Ca group) or with prebiotic oligofructose-enriched inulin supplemented diet until the end of the lactation period. At weaning, bone mineral content (BMC) and BMD were determined by dual-energy X-ray absorptiometry and the pH of the cecal content was also determined. Results: In absolute terms, the highest BMD and BMC were found in the Pre group as compared with the other two groups being signifi cant in the tibia when compared Pre group and CC group with Ca group. The pH of the cecal content in the Pre group was also signifi cantly lower as compared with the other two groups. Conclusion: Prebiotic oligofructose-enriched inulin supplementation, in calcium no-defi cient conditions, during gestation and lactation exerts a protection on maternal skeleton during pregnancy and lactation in the rats and could be considered as a plausible nutritional option for protecting maternal bone mass during these periods.