Influencia de los factores climáticos en la incidencia de hemorragia digestiva alta

López-Cepero, Jesús; López-Silva, MC; Amaya-Vidal, Antonio; Alcaraz-García, S.; Cayon-Blanco, Manuel; Castro, Teresa; Esteban-Álvarez, A.I.; Ferré-Álamo, A.; Benítez-Roldán, A.

doi:10.1157/13080601

Cited by 8 publications

(12 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As for hemorrhage, autumn or winter peaks have been found again in the USA [27], Russia [28], Taiwan [29,30], and Japan [31]. Thomopoulos et al [32] in Greece, Yen et al [33] in Taiwan, and Rodriguez et al in Mexico [34] found summer/autumn peaks, while Lopez-Cepero et al [35] in Spain found no seasonality, and in Norway Svanes et al [36] reported a 6-month time pattern. A different seasonal variation, with spring-summer peaks, was reported in Australia [37], Denmark [38], and Poland [39].…”

Section: Discussionmentioning

confidence: 99%

“…A recent nation-wide study conducted in Taiwan by Xirasagar et al [46] found DU admissions were negatively associated with temperature, with a winter peak and summer trough in patients 35-49 and >50 yrs of age. On the other hand, a Spanish study [35] failed to find a correlation between the incidence of GU bleeding and ambient temperature, atmospheric pressure, relative humidity, wind direction and speed.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Seasonal pattern of peptic ulcer hospitalizations: analysis of the hospital discharge data of the Emilia-Romagna region of Italy

et al. 2010

View full text Add to dashboard Cite

BackgroundPrevious studies have reported seasonal variation in peptic ulcer disease (PUD), but few large-scale, population-based studies have been conducted.MethodsTo verify whether a seasonal variation in cases of PUD (either compicated or not complicated) requiring acute hospitalization exists, we assessed the database of hospital admissions of the region Emilia Romagna (RER), Italy, obtained from the Center for Health Statistics, between January 1998 and December 2005. Admissions were categorized by sex, age (<65, 65-74, ≥ 75 yrs), site of PUD lesion (stomach or duodenum), main complication (hemorrhage or perforation), and final outcome (intended as fatal outcome: in-hospital death; nonfatal outcome: patient discharged alive). Temporal patterns in PUD admissions were assessed in two ways, considering a) total counts per single month and season, and b) prevalence proportion, such as the monthly prevalence of PUD admissions divided by the monthly prevalence of total hospital admissions, to assess if the temporal patterns in the raw data might be the consequence of seasonal and annual variations in hospital admissions per se in the region. For statistical analysis, the χ2 test for goodness of fit and inferential chronobiologic method (Cosinor and partial Fourier series) were used.ResultsOf the total sample of PUD patients (26,848 [16,795 males, age 65 ± 16 yrs; 10,053 females, age 72 ± 15 yrs, p < 0.001)], 7,151 were <65 yrs of age, 8,849 between 65 and 74 yrs of age, and 10,848 ≥ 75 yrs of age. There were more cases of duodenal (DU). (89.8%) than gastric ulcer (GU) (3.6%), and there were 1,290 (4.8%) fatal events. Data by season showed a statistically difference with the lowest proportion of PUD hospital admissions in summer (23.3%) (p < 0.001), for total cases and rather all subgroups. Chronobiological analysis identified three major peaks of PUD hospitalizations (September-October, January-February, and April-May) for the whole sample (p = 0.035), and several subgroups, with nadir in July. Finally, analysis of the monthly prevalence proportions yielded a significant (p = 0.025) biphasic pattern with a main peak in August-September-October, and a secondary one in January-February.ConclusionsA seasonal variation in PUD hospitalization, characterized by three peaks of higher incidence (Autumn, Winter, and Spring) is observed. When data corrected by monthly admission proportions are analyzed, late summer-autumn and winter are confirmed as higher risk periods. The underlying pathophysiologic mechanisms are unknown, and need further studies. In subjects at higher risk, certain periods of the year could deserve an appropriate pharmacological protection to reduce the risk of PUD hospitalization.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Seasonal pattern of peptic ulcer hospitalizations: analysis of the hospital discharge data of the Emilia-Romagna region of Italy

et al. 2010

View full text Add to dashboard Cite

show abstract

“…But it's controversial reports. Lopez-Cepero and his colleague [8] used retrospective analysis to study the 499 cases with upper gastrointestinal hemorrhage in Jerez de la Frontera of Spain, including 108 cases with esophagogastric variceal bleeding. They found that there was no relationship between the onset of bleeding and seasonal variation and meteorological factors (temperature, air pressure, humidity, wind direction and air speed).…”

Section: Dicussionmentioning

confidence: 99%

Influence of meteorological factors on the seasonal onset of esophagogastric variceal bleeding

Chen¹,

Li²,

Shu³

et al. 2013

OJGas

View full text Add to dashboard Cite

Purpose: To investigate the influence of meteorological factors on the esophagogastric variceal bleeding. The rhythmicity and variation mechanism of the onset of esophagogastric variceal bleeding were determined by large sample study. Methods: 572 patients with esophagogastric variceal bleeding confirmed by endoscopy were enrolled in the study, and the gender, age, onset date and Child-Pugh grading of liver function were recorded, the meteorological data were provided by the Shiyan Meteorological Bureau, which included temperature, air pressure, air speed, precipitation, sunshine duration and so on. Results: The onset numbers in the four seasons were 130, 122, 144 and 176, respectively, and differences of the onset number in different seasons were significant (X2 = 11.888, p = 0.008), and the onset number in winter reached to maximum, while it decreased to minimum in summer. The results of Child-Pugh grading were as follows: Grade A 113 (19.8%), Grade B 234 (40.9%), and Grade C 225 (39.3%). There was no significance among the different grades by crosstabs analysis (X2 = 4.463, p = 0.107). The Spearman correlation analysis concluded the result of (r > 0 and p < 0.01) in the air pressure (mean, maximal and minimal), daily mean temperature, ten days’ air pressure (mean, daily difference, maximal, minimal and range), ten days’ temperature range on the onset day, while the result of (r < 0 and p < 0.01) in the daily maximal temperature, daily minimal temperature, ten days’ temperature (mean, maximal and minimal) and ten days’ ≥0?C accumulated temperature. The p value was more than0.01 inthe other factors. Conclusion: The onset of esophagogastric variceal bleeding was rhythmical, which rose to the maximum in winter and decreased to minimum in summer. The onset of the disease correlated positively with daily air pressure (mean, maximal, minimal), daily mean temperature, ten days’ air pressure (mean, daily difference, maximal, minimal and range) and ten days’ temperature range, and correlated negatively with daily maximal temperature, daily minimal temperature, ten days’ temperature (mean, maximal and minimal) and ten days’ ≥0°C accumulated temperature, and had no relationship with other factors. The mechanism of the onset may associate with the increase of portal venous flow through vasoconstriction induced by chill factors....

show abstract

“…Seasonal variations in AGIB have rarely been studied, and the published results tend to be contradictory. Higher incidences of upper GIB (UGIB) have been reported in winter and spring (Tsai & Lin 1998, Sezgin et al 2007, Du et al 2010), whereas others have described a decreased incidence in winter, or no seasonal fluctuations at all (López-Cepero et al 2005). A significant relationship has been demonstrated between winter and the incidence of peptic ulcers (Yuan et al 2015) and the incidence of duodenal ulcers, but not the incidence of gastric ulcers (Stermer et al 1995).…”

Section: Introductionmentioning

confidence: 99%

“…The publications in which the relationships between AGIB and climatic factors were examined generally related to Mediterranean (Grassi et al 1993, Thomopoulos et al 1997, Tenías Burillo et al 2001, López-Cepero et al 2005, Sezgin et al 2007 or subtropical climates (Stermer et al 1995, Yen et al 1996, Tsai & Lin 1998, Nomura et al 2001, Du et al 2010. No study has been reported on the effects of a continental climate on AGIB.…”

Section: Introductionmentioning

confidence: 99%

Effects of a continental climate on the prevalence and severity of acute non-variceal gastrointestinal bleeding

et al. 2017

View full text Add to dashboard Cite

Seasonal variations in acute gastrointestinal bleeding (AGIB) have rarely been studied, and the published results tend to be contradictory. The aim of this study was to determine the relation between changes in meteorological conditions and the occurrence and severity of AGIB in a continental climate. A retrospective analysis of hospital admissions for AGIB (n = 1033 patients) between 1 January 2010 and 31 December 2012 took into consideration meteorological data obtained from the Hungarian National Meteorology Service. The severity of AGIB and ulcer bleeding was determined by the Glasgow Blatchford score (GBS) and the Forrest classification. No correlations were revealed regarding the monthly and seasonal fluctuations of AGIB, but we did find a significant correlation between the occurrence of AGIB and daily mean temperature. Humidity correlated significantly with the severity of upper gastrointestinal bleeding (UGIB), and meteorological front movement rates were correlated with the number of lower gastrointestinal bleeding (LGIB) cases. Data showed no significant correlations between gastric and duodenal ulcers and climatic factors such as front movement rates, atmospheric pressure, humidity, daily mean temperature and the presence of a full moon. KEY WORDS: Daily mean temperature • Front movement rate • Ulcer • Humidity • Acute non-variceal gastrointestinal bleeding • Climatic factors Resale or republication not permitted without written consent of the publisher This authors' personal copy may not be publicly or systematically copied or distributed, or posted on the Open Web, except with written permission of the copyright holder(s). It may be distributed to interested individuals on request.

show abstract

Influencia de los factores climáticos en la incidencia de hemorragia digestiva alta

Cited by 8 publications

References 16 publications

Seasonal pattern of peptic ulcer hospitalizations: analysis of the hospital discharge data of the Emilia-Romagna region of Italy

Seasonal pattern of peptic ulcer hospitalizations: analysis of the hospital discharge data of the Emilia-Romagna region of Italy

Influence of meteorological factors on the seasonal onset of esophagogastric variceal bleeding

Effects of a continental climate on the prevalence and severity of acute non-variceal gastrointestinal bleeding

Contact Info

Product

Resources

About